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57337 SENP7

57337

SENP7

SUMO specific peptidase 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition SUMO specific peptidase 7

研究结论

Date Results Publications
2020-09-26 13:06:00 DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells. 31825833
2019-07-27 11:03:00 non-tumorigenic MCF10-2A cells with reduced SENP7S exhibit greater cell proliferation and anchorage-dependent growth. SENP7S depletion directly potentiates tumorigenic properties of MCF10-2A cells with induction of anchorage-independent growth and self-renewal in 3D-spheroid conditions. Collectively, the results identify SENP7S as a novel mediator of beta-catenin signaling and normal mammary epithelial cell physiology. 28429743
2018-11-10 10:31:00 SPOP inhibits hepatocellular carcinoma (HCC) cell metastasis via ubiquitin-dependent SENP7 proteolysis and may thus serve as a new opinion for the prevention of HCC metastasis. 29777712
2016-04-23 11:52:00 c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4 25895136
2014-07-19 13:04:00 deSUMOylation by SENP7 is required to promote a permissive chromatin environment for DNA repair. 24018422

名称对应

Type IDs
Gene
UniProtKB-ID: SENP7_HUMAN, J3QT09_HUMAN
UniprotKB: Q9BQF6, J3QT09
UniParc: UPI000002B362, UPI000013D130, UPI0000E56ED1, UPI000013F798, UPI00001A9D2D, UPI000013EF9B
EMBL: AB051494, AF199458, AC110994, BX537943, AC073861, AL136599, AC068764, AF217504, BC129988
Ensembl: ENSG00000138468
KO: hsa:57337
Nucleutide sequences
EMBL-CDS: BAB21798.1, CAD97911.1, CAB66534.1, AAI29989.1, AAL25651.1, AAG09703.1
Ensembl_TRS: ENST00000394095, ENST00000394091, ENST00000314261, ENST00000394085, ENST00000348610, ENST00000394094
Protein sequencees
Ensembl_PRO: ENSP00000377651, ENSP00000377647, ENSP00000342159, ENSP00000313624, ENSP00000377655, ENSP00000377654
RefSeq: NP_065705.3, XP_016862415.1, NP_001070671.1, XP_016862417.1, XP_011511340.1, XP_016862414.1, NP_001269730.1, XP_005247719.1, NP_001269733.1, XP_016862413.1, XP_011511347.1, XP_016862416.1, XP_016862418.1, XP_011511342.1, NP_001269731.1, XP_011511341.1, NP_001269732.1, XP_011511344.1, XP_011511343.1
Others
UniRef100: UniRef100_J3QT09, UniRef100_Q9BQF6
UniRef90: UniRef90_Q9BQF6, UniRef90_A0A2K5LTN6
UniRef50: UniRef50_Q9BQF6
UniGene: Hs.529551
CCDS: CCDS63706.1, CCDS63704.1, CCDS63705.1, CCDS2941.2

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