| Type | Description |
|---|---|
| Definition | chromobox 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:53:00 | Optimization of Ligands Using Focused DNA-Encoded Libraries To Develop a Selective, Cell-Permeable CBX8 Chromodomain Inhibitor. | 31755685 |
| 2020-09-05 13:57:00 | Chromobox homolog 8 (CBX8) Interacts with Y-Box binding protein 1 (YBX1) to promote cellular proliferation in hepatocellular carcinoma cells. | 31495785 |
| 2020-04-04 10:40:00 | Results establish CBX8 as a critical driver of HCC stem cell-like and metastatic behaviors and characterize its role in modulating BMP4 expression. | 30718464 |
| 2019-10-12 12:26:00 | function of the CBX8 chromodomain (CD) in vitro and in vivo; the CD is in fact a major driver of CBX8 chromatin association and this is driven by both histone and previously unrecognized DNA binding activity; characterization of the structural basis of histone and DNA binding and determine how they integrate on multiple levels | 30597065 |
| 2019-08-03 10:32:00 | Report shows that CBX8 is upregulated in esophageal squamous cell carcinoma (ESCC) tissues and cells and serves as an indicator of poor prognosis for ESCC patients. CBX8 knockdown inhibits cell proliferation, colony formation capability, DNA repair and promotes cell apoptosis. | 31255735 |
| Type | IDs |
|---|---|
| Synonymous | PC3, RC1 |
| Gene |
UniProtKB-ID:
CBX8_HUMAN
UniprotKB:
Q9HC52
UniParc:
UPI000013D82A
EMBL:
AK074560,
BC008937,
BC009376,
BC019289,
AF266479,
AF174482
Ensembl:
ENSG00000141570
KO:
hsa:57332
|
| Nucleutide sequences |
EMBL-CDS:
AAH19289.1,
AAF76328.2,
AAH08937.1,
BAC11061.1,
AAG09180.1,
AAH09376.1
Ensembl_TRS:
ENST00000269385
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000269385
RefSeq:
NP_065700.1
|
| Others |
UniRef100:
UniRef100_Q9HC52
UniRef90:
UniRef90_Q9HC52
UniRef50:
UniRef50_Q9HC52
UniGene:
Hs.387258
CCDS:
CCDS11765.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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