| Type | Description |
|---|---|
| Definition | Parkinson disease (autosomal recessive, early onset) 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:30:00 | Unveiling the Role of DJ-1 Protein in Vesicular Storage and Release of Catecholamine with Nano/Micro-Tip Electrodes. | 32249515 |
| 2020-12-12 13:25:00 | Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53. | 32075910 |
| 2020-11-28 13:14:00 | Protective role of DJ-1 in endotoxin-induced acute kidney injury. | 32715759 |
| 2020-08-13 13:43:00 | Deletion of DJ -1 leads to oxidative stress-induced hypertension associated with downregulation of NO function, and overexpression of Ucp2 in the kidney increases blood pressure in DJ -1 (-/-) mice. | 30995881 |
| 2020-07-11 11:03:00 | Inhibition of DJ-1 potently enhances the sensitivity of tumor cells to ferroptosis inducers both in vitro and in vivo. Metabolic analysis and metabolite rescue assay reveal that DJ-1 depletion inhibits the transsulfuration pathway by disrupting the formation of the S-adenosyl homocysteine hydrolase tetramer and impairing its activity. Study findings show that DJ-1 determines the response of cancer cells to ferroptosis. | 32144268 |
| Type | IDs |
|---|---|
| Synonymous | DJ-1, Dj1 |
| Gene |
UniProtKB-ID:
PARK7_MOUSE
UniprotKB:
Q99LX0
UniParc:
UPI0000027D8D
EMBL:
AK153948,
AK168341,
AB015652,
AL607084,
BC002187,
AK146368
Ensembl:
ENSMUSG00000028964
KO:
mmu:57320
|
| Nucleutide sequences |
EMBL-CDS:
BAE27118.1,
BAE40278.1,
BAA29063.2,
BAE32271.1,
AAH02187.1
Ensembl_TRS:
ENSMUST00000030805,
ENSMUST00000105675,
ENSMUST00000105674,
ENSMUST00000105673
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000101300,
ENSMUSP00000030805,
ENSMUSP00000101299,
ENSMUSP00000101298
RefSeq:
NP_065594.2,
XP_036020176.1
|
| Others |
UniRef100:
UniRef100_Q99LX0
UniRef90:
UniRef90_Q99LX0
UniRef50:
UniRef50_Q99LX0
UniGene:
Mm.277349
CCDS:
CCDS18975.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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