| Type | Description |
|---|---|
| Definition | protease, serine 21 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:48:00 | Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis. | 32511276 |
| 2020-06-27 10:17:00 | Testisin inhibits metastatic ovarian tumor burden and ascites production. Testisin activity antagonizes ANG2 and ANGPTL4 synthesis and secretion. | 30911775 |
| 2012-12-22 10:47:00 | ACR or PRSS21 or both may function cooperatively with in sperm/cumulus penetration | 22362218 |
| 2010-12-04 10:18:00 | These data demonstrate that the trypsinlike protease activity of ACR and PRSS21 is essential for the process of sperm penetration through the cumulus matrix and zona pellucida in vitro | 20484738 |
| 2010-01-21 00:00:00 | The reduced fertility of Prss21-null epididymal sperm was rescued by exposure of the sperm to the uterine microenvironment and by in vitro treatment of the sperm with uterine fluids. | 18754795 |
| Type | IDs |
|---|---|
| Synonymous | 1700023E12Rik, TESP5, mT4, testisin |
| Gene |
UniProtKB-ID:
TEST_MOUSE,
Q80YD8_MOUSE,
Q54AE4_MOUSE
UniprotKB:
Q9JHJ7,
Q80YD8,
Q54AE4
UniParc:
UPI0000000CE2,
UPI0000185E47
EMBL:
AF176209,
BC116755,
BC049588,
AK006271,
AF226710,
AB059415,
AB059414,
AY005145,
AB041645,
AB033822,
BC116757,
AF304012
Ensembl:
ENSMUSG00000024116
KO:
mmu:57256
|
| Nucleutide sequences |
EMBL-CDS:
AAF64428.2,
AAF64407.2,
AAK29360.1,
AAG02255.1,
AAH49588.1,
AAI16758.1,
BAB61788.1,
BAB16701.1,
AAI16756.1,
BAB64263.1,
BAB61787.1
Ensembl_TRS:
ENSMUST00000024928
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024928
RefSeq:
NP_065233.2
|
| Others |
UniRef100:
UniRef100_Q9JHJ7
UniRef90:
UniRef90_Q9JHJ7
UniRef50:
UniRef50_Q9JHJ7
UniGene:
Mm.386785
CCDS:
CCDS28468.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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