| Type | Description |
|---|---|
| Definition | adhesion G protein-coupled receptor G6 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 12:25:00 | Asymmetric expression of GPR126 in the convex/concave side of the spine is associated with spinal skeletal malformation in adolescent idiopathic scoliosis population | 31079250 |
| 2020-05-09 12:51:00 | modulation of gpr126 expression in zebrafish by injection of either miR-27b or miR-27b inhibitor in single cell-stage embryos resulted in hypo- or hypertrabeculation, respectively | 31596512 |
| 2020-05-09 11:19:00 | data demonstrate that the newly generated lacZ reporter mouse is a suitable model to study Gpr126 expression during development and adulthood, provide detailed insight into Gpr126 expression at the cellular level, and reveal that all identified Gpr126-expressing cells are known to be exposed to mechanical stimuli | 31215653 |
| 2020-04-04 11:43:00 | Alternative splicing regulates ECR conformation and receptor signaling, while mutagenesis of the calcium-binding site abolishes Gpr126 function in vivo. These results demonstrate that Gpr126 ECR utilizes a multi-faceted dynamic approach to regulate receptor function and provide relevant insights for ECR-targeted drug design. | 31924782 |
| 2020-02-15 13:45:00 | The role of GPR126 in radial sorting and myelination in Schwann cells suggests a mechanism of pathogenesis for intellectual disability (ID). Involvement of GPR126 in lethal congenital contracture syndrome 9 has been identified previously, but this is the first report of a plausible candidate gene, GPR126, in ID. | 30549416 |
| Type | IDs |
|---|---|
| Synonymous | APG1, DREG, GPR126, LCCS9, PR126, PS1TP2, VIGR |
| Gene |
UniProtKB-ID:
AGRG6_HUMAN
UniprotKB:
Q86SQ4
UniParc:
UPI000020E324,
UPI000022CCE5,
UPI000022CCE4,
UPI000046FFCF
EMBL:
AL033377,
AF216967,
AY181244,
AK075087,
AB183549,
AB183547,
AB183546,
AY426673,
BC075798,
BX640873,
AK027843,
AB183548,
BX640971,
AL360007
Ensembl:
ENSG00000112414
KO:
hsa:57211
|
| Nucleutide sequences |
EMBL-CDS:
AAR88427.1,
CAE45930.1,
BAB55406.1,
BAD27574.1,
CAE45986.1,
BAD27573.1,
BAC11393.1,
BAD27572.1,
AAO27356.1,
BAD27571.1,
AAH75798.1,
AAO13250.1
Ensembl_TRS:
ENST00000296932,
ENST00000230173,
ENST00000367609,
ENST00000367608
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296932,
ENSP00000356581,
ENSP00000230173,
ENSP00000356580
RefSeq:
XP_006715580.1,
NP_940971.2,
XP_011534266.1,
NP_001027567.2,
XP_005267118.1,
XP_016866574.1,
NP_065188.5,
XP_006715579.1,
XP_006715581.1,
NP_001027566.2
|
| Others |
UniRef100:
UniRef100_Q86SQ4
UniRef90:
UniRef90_Q86SQ4
UniRef50:
UniRef50_Q86SQ4
UniGene:
Hs.743302
CCDS:
CCDS47489.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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