| Type | Description |
|---|---|
| Definition | mucolipin 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:30:00 | Genome-wide scan identifies opioid overdose risk locus close to MCOLN1. | 31362332 |
| 2021-02-02 13:24:00 | Long-term observation of a Japanese mucolipidosis IV patient with a novel homozygous p.F313del variant of MCOLN1. | 32220057 |
| 2020-10-24 14:11:00 | Mitochondria-lysosome contacts regulate mitochondrial Ca(2+) dynamics via lysosomal TRPML1. | 32703809 |
| 2020-08-29 12:47:00 | TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling. | 31461647 |
| 2020-07-25 12:03:00 | the lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways | 30889511 |
| Type | IDs |
|---|---|
| Synonymous | MG-2, ML1, ML4, MLIV, MST080, MSTP080, TRP-ML1, TRPM-L1, TRPML1 |
| Gene |
UniProtKB-ID:
MCLN1_HUMAN
UniprotKB:
Q9GZU1
UniParc:
UPI00000377A2
EMBL:
AF305573,
AF171088,
CH471139,
AF305572,
AF305576,
AF305575,
AF305577,
AJ293659,
AF305578,
AK026102,
AF305579,
BC005149,
AF287269,
AF249319,
AF305574,
AJ293970,
AF287270
Ensembl:
ENSG00000090674
KO:
hsa:57192
|
| Nucleutide sequences |
EMBL-CDS:
CAC07813.1,
AAG10422.1,
EAW69034.1,
CAC08215.1,
AAG00797.1,
AAG42242.1,
BAB15360.1,
AAG00798.1,
AAH05149.1,
AAQ13604.1,
EAW69031.1
Gene_ORFName:
MSTP080
Ensembl_TRS:
ENST00000264079
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264079
RefSeq:
NP_065394.1
|
| Others |
UniRef100:
UniRef100_Q9GZU1
UniRef90:
UniRef90_Q9GZU1
UniRef50:
UniRef50_Q9GZU1
UniGene:
Hs.631858
CCDS:
CCDS12180.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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