| Type | Description |
|---|---|
| Definition | RAB8A, member RAS oncogene family |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:20:00 | While localization of the small GTPase Rab8a, which plays an important role in basal body docking, appears unaffected in talpid3-/- photoreceptors, overexpression of constitutively active Rab8a rescues outer segment formation, indicating that the role of Ta3 in early ciliogenesis lies upstream of Rab8a activation in photoreceptors. | 29396404 |
| 2018-03-03 11:07:00 | Results support participation of Rab8 in OCV trafficking and identify a novel role for the TZ protein Cc2d2a in fusion of incoming ciliary-directed vesicles, through organization of the vesicle fusion machinery at the periciliary membrane. | 29281629 |
| 2012-01-28 12:24:00 | Cc2d2a, localized at the photoreceptor connecting cilium/transition zone, facilitates protein transport through a role in Rab8-dependent vesicle trafficking and fusion. | 21816947 |
| 2010-01-21 00:00:00 | Data show that elipsa encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8, a small GTPase, known to localize to cilia. | 18364699 |
| Type | IDs |
|---|---|
| Synonymous | rab8, zgc:162699 |
| Gene |
UniProtKB-ID:
A4FVK4_DANRE
UniprotKB:
A4FVK4
UniParc:
UPI0000F57F14
EMBL:
CU693492,
BC134059
Ensembl:
ENSDARG00000067920
KO:
dre:571897
|
| Nucleutide sequences |
EMBL-CDS:
AAI34060.1
Ensembl_TRS:
ENSDART00000149062,
ENSDART00000186404
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000125104,
ENSDARP00000149394
RefSeq:
NP_001083031.1
|
| Others |
UniRef100:
UniRef100_A4FVK4
UniRef90:
UniRef90_A4FVK4
UniRef50:
UniRef50_Q94148
UniGene:
Dr.133969
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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