| Type | Description |
|---|---|
| Definition | THO complex 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 11:26:00 | THOC2 reduction repressed melanoma cell proliferation and invasion, and induced cell apoptosis. | 31680623 |
| 2019-07-20 10:20:00 | Study presents detailed clinical assessment and functional studies on a de novo variant in a female with an epileptic encephalopathy and discuss an additional four families with rare variants in THOC2 with supportive evidence for pathogenicity. | 29851191 |
| 2015-10-31 11:16:00 | THOC2 mutations implicate mRNA-export pathway in X-linked intellectual disability. | 26166480 |
| 2010-01-21 00:00:00 | recruitment of the human TREX complex to spliced mRNA is not directly coupled to transcription, but is instead coupled to transcription indirectly through splicing | 15998806 |
| Type | IDs |
|---|---|
| Synonymous | CXorf3, MRX12, MRX35, THO2, dJ506G2.1, hTREX120 |
| Gene |
UniProtKB-ID:
THOC2_HUMAN
UniprotKB:
Q8NI27
UniParc:
UPI00001D7C42,
UPI000037834A
EMBL:
Z82901,
AL023575,
BC072400,
AF441770,
AL030996,
BX648654,
AK023659
Ensembl:
ENSG00000125676
KO:
hsa:57187
|
| Nucleutide sequences |
EMBL-CDS:
CAI42271.2,
BAB14630.1,
CAO03594.1,
CAI42864.2,
AAH72400.1,
CAE46196.1,
AAM28436.1
Ensembl_TRS:
ENST00000245838,
ENST00000355725,
ENST00000618150
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000480478,
ENSP00000245838,
ENSP00000347959
RefSeq:
XP_016885151.1,
XP_016885165.1,
XP_016885153.1,
XP_016885168.1,
XP_016885152.1,
XP_016885156.1,
XP_016885164.1,
XP_016885154.1,
XP_016885161.1,
NP_001075019.1,
XP_016885157.1
|
| Others |
UniRef100:
UniRef100_Q8NI27
UniRef90:
UniRef90_Q8NI27
UniRef50:
UniRef50_Q8NI27
UniGene:
Hs.149991
CCDS:
CCDS43988.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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