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57132 CHMP1B

57132

CHMP1B

charged multivesicular body protein 1B

protein-coding

Homo sapiens

基因描述

Type Description
Definition charged multivesicular body protein 1B

研究结论

Date Results Publications
2020-07-18 12:23:00 To learn how certain ESCRT-IIIs shape positively curved membranes, we determined structures of human membrane-bound CHMP1B-only, membrane-bound CHMP1B + IST1, and IST1-only filaments by cryo-EM 32251413
2012-06-09 11:23:00 The interaction between CL7MIT and CHMP1B and between CL7MIT and IST1 became stronger when IST1 or CHMP1B was additionally coexpressed, suggesting formation of ternary complex of calpain-7, IST1 and CHMP1B. 21616915
2010-01-21 00:00:00 CHMP1B is bound by the VPS4A microtubule interacting and transport (MIT) domain. 16174732
2010-01-21 00:00:00 The 2.5-A structure of the C-terminal tail of CHMP1B with the MIT domain of spastin reveals a specific, high-affinity complex involving a noncanonical binding site between the first and third helices of the MIT domain. 18997780
2010-01-21 00:00:00 UBPY MIT domain and another ubiquitin isopeptidase, AMSH, reveals common interactions with CHMP1A and CHMP1B but a distinct selectivity of AMSH for CHMP3/VPS24, a core subunit of the ESCRT-III complex, and UBPY for CHMP7. 17711858

名称对应

Type IDs
Synonymous C10orf2, C18-ORF2, C18orf2, CHMP1.5, Vps46-2, Vps46B, hVps46-2
Gene
UniProtKB-ID: CHM1B_HUMAN
UniprotKB: Q7LBR1
UniParc: UPI00000373BD
EMBL: BC012733, AF281064, BC065933, AF306520
Ensembl: ENSG00000255112
KO: hsa:57132
Nucleutide sequences
EMBL-CDS: AAG01449.1, AAL48200.1, AAH65933.1, AAH12733.3
Ensembl_TRS: ENST00000526991
Protein sequencees
Ensembl_PRO: ENSP00000432279
RefSeq: NP_065145.2
Others
UniRef100: UniRef100_Q7LBR1
UniRef90: UniRef90_Q7LBR1
UniRef50: UniRef50_Q7LBR1
UniGene: Hs.656244
CCDS: CCDS54180.1

全选

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