| Type | Description |
|---|---|
| Definition | LYR motif containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 10:50:00 | In this work, the structure of the human mitochondrial ACP-ISD11 heterodimer was determined at 2.0 A resolution. | 31664822 |
| 2019-08-10 11:55:00 | The molecular structure of the human mitochondrial cysteine desulfurase complex consisting of two copies each of NFS1, ISD11, and acyl carrier protein has been described. | 29983374 |
| 2018-06-09 12:05:00 | analysis of the NFS1-ISD11-ACP (SDA) complex forms the core of the iron-sulfur (Fe-S) assembly complex and associates with assembly proteins ISCU2, frataxin (FXN), and ferredoxin to synthesize Fe-S clusters | 28634302 |
| 2017-07-29 10:38:00 | Human Isd11 (ISD11) is a helical protein which exists in solution as an equilibrium between monomer, dimeric and tetrameric species when in the absence of human Nfs1 (NFS1). Recombinant ISD11 expressed in E. coli co-purifies with the bacterial orthologue of NFS1, IscS. | 27427956 |
| 2017-06-03 11:44:00 | The NFS1/ISD11 complex further interacts with scaffold protein ISCU and regulator protein frataxin, thereby forming a quaternary complex for Fe-S cluster formation. | 28271877 |
| Type | IDs |
|---|---|
| Synonymous | C6orf149, CGI-203, COXPD19, ISD11 |
| Gene |
UniProtKB-ID:
LYRM4_HUMAN,
F5H189_HUMAN,
C9JY28_HUMAN,
C9JRX8_HUMAN
UniprotKB:
Q9HD34,
F5H189,
C9JY28,
C9JRX8
UniParc:
UPI0001892A6B,
UPI000006F715,
UPI0001B71BCB,
UPI000041562F
EMBL:
AL121978,
AK291158,
KF458083,
KF510955,
AL035653,
AF170070,
AF285118,
BC009552,
AL162381,
KF458082
Ensembl:
ENSG00000214113
KO:
hsa:57128
|
| Nucleutide sequences |
EMBL-CDS:
AAF25797.1,
AAH09552.1,
BAF83847.1,
AAG01155.1
Gene_ORFName:
CGI-203
Ensembl_TRS:
ENST00000330636,
ENST00000500576,
ENST00000480566,
ENST00000464010
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418787,
ENSP00000443900,
ENSP00000419928,
ENSP00000420026
RefSeq:
NP_001158312.1,
NP_001305712.1,
XP_016866573.1,
NP_065141.3,
XP_016866572.1,
NP_001305711.1,
NP_001158313.1
|
| Others |
UniRef100:
UniRef100_C9JY28,
UniRef100_C9JRX8,
UniRef100_F5H189,
UniRef100_Q9HD34
UniRef90:
UniRef90_C9JRX8,
UniRef90_Q9HD34,
UniRef90_A0A2I2Y8E0,
UniRef90_C9JY28
UniRef50:
UniRef50_Q9HD34,
UniRef50_A0A2I2Y8E0,
UniRef50_C9JY28
UniGene:
Hs.387755
CCDS:
CCDS4493.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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