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57121 LPAR5

57121

LPAR5

lysophosphatidic acid receptor 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition lysophosphatidic acid receptor 5

研究结论

Date Results Publications
2021-04-13 10:13:00 LPAR5 promotes thyroid carcinoma cell proliferation and migration by activating class IA PI3K catalytic subunit p110beta. 33540491
2021-01-09 13:33:00 Lysophosphatidic acid receptor 5 transactivation of TGFBR1 stimulates the mRNA expression of proteoglycan synthesizing genes XYLT1 and CHST3. 32920014
2020-08-22 15:25:00 LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling. 31231367
2020-06-13 11:40:00 LPAR5 expression was elevated in A375cells treated with anticancer drugs. The high cell survival of highly migratory A375cells is associated with the low LPAR5 expression. The cell survival of A375cells treated with anticancer drugs was increased by LPA5 knockdown. 31362892
2020-06-06 10:23:00 Downregulation of LPAR5 expression can inhibit the physiological process of PTC, and this phenomenon is related to the PI3K/AKT pathway and EMT. 31902939

名称对应

Type IDs
Synonymous GPR92, GPR93, KPG_010, LPA5
Gene
UniProtKB-ID: LPAR5_HUMAN, Q5KU18_HUMAN
UniprotKB: Q9H1C0, Q5KU18
UniParc: UPI0000036A45
EMBL: HQ995529, AF411112, AB083600, AB041943, BC033571, CH471116, AK313127, BC072394, AJ272207
Ensembl: ENSG00000184574
KO: hsa:57121
Nucleutide sequences
EMBL-CDS: CAC03715.1, AAH72394.1, BAB89313.1, AAL26483.1, AAH33571.1, EAW88775.1, EAW88776.1, ADZ31974.1, BAD83597.1, BAG35947.1
Gene_ORFName: hCG_2039707
Ensembl_TRS: ENST00000329858, ENST00000431922
Protein sequencees
Ensembl_PRO: ENSP00000393098, ENSP00000327875
RefSeq: NP_001136433.1, NP_065133.1
Others
UniRef100: UniRef100_Q9H1C0
UniRef90: UniRef90_Q9H1C0
UniRef50: UniRef50_Q9H1C0
UniGene: Hs.155538
CCDS: CCDS8553.1

全选

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