| Type | Description |
|---|---|
| Definition | RAB25, member RAS oncogene family |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 10:58:00 | Loss of Rab25 promotes the development and neoplastic transition of skin squamous cell carcinoma through dysregulation of integrin trafficking. | 31144312 |
| 2019-07-06 10:12:00 | Promoter DNA methylation analysis reveals a novel diagnostic CpG-based biomarker and RAB25 hypermethylation in clear cell renel cell carcinoma | 29079774 |
| 2019-06-23 00:09:00 | Rab25 overexpression induced erlotinib resistance, whereas Rab25 knockdown reversed this refractoriness in vitro and in vivo. Moreover, Rab25 interacts with beta1 integrin and promotes its trafficking to the cytoplasmic membrane. | 30848009 |
| 2019-01-26 12:41:00 | Rab25 modulates cancer cell invasion through coordinated regulation of beta1-integrin to activation of EGFR and expression of VEGF-A to increase the level of Snail protein and subsequent Fascin expression. | 29371698 |
| 2018-12-29 10:47:00 | ZEB2 directly binds to E-box sequences in the RAB25 promoter.ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 during epithelial-to-mesenchymal transition. | 30445998 |
| Type | IDs |
|---|---|
| Synonymous | CATX-8, RAB11C |
| Gene |
UniProtKB-ID:
RAB25_HUMAN
UniprotKB:
P57735
UniParc:
UPI0000073C4C
EMBL:
BC033322,
AF274025,
AF083124,
CH471121,
BC009831,
AL355388,
BC004416
Ensembl:
ENSG00000132698
KO:
hsa:57111
|
| Nucleutide sequences |
EMBL-CDS:
AAF98238.1,
AAH04416.1,
EAW53003.1,
AAM69362.1,
AAH33322.1,
AAH09831.1
Ensembl_TRS:
ENST00000361084
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354376
RefSeq:
NP_065120.2
|
| Others |
UniRef100:
UniRef100_P57735
UniRef90:
UniRef90_P57735
UniRef50:
UniRef50_P57735
UniGene:
Hs.632469
CCDS:
CCDS41413.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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