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5711 PSMD5

5711

PSMD5

proteasome 26S subunit, non-ATPase 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition proteasome 26S subunit, non-ATPase 5

研究结论

Date Results Publications
2019-08-10 12:39:00 Study in HT-29 cells and mouse colorectal tumor models revealed that levels of the proteasome assembly inhibitor PSMD5/S5B are significantly decreased in tumors, and re-expression of PSMD5 blocks 26S proteasome assembly. These results suggest that intestinal cancer cells escape proteotoxic stress by reducing PSMD5 to stimulate 26S proteasome assembly. 29716915
2013-03-02 13:17:00 the critical role of S5b/PSMD5 in negative regulation of proteasome by TNF-alpha/NFkappaB and provide insights into proteasome inhibition in human disease. 22921402

名称对应

Type IDs
Synonymous S5B
Gene
UniProtKB-ID: PSMD5_HUMAN
UniprotKB: Q16401
UniParc: UPI00017A848D, UPI0000132785
EMBL: AL161911, BC014478, AK303007, CH471090, D31889, S79862
Ensembl: ENSG00000095261
KO: hsa:5711
Nucleutide sequences
EMBL-CDS: AAH14478.1, EAW87471.1, BAG64140.1, AAB35397.1, BAA06687.1
Ensembl_TRS: ENST00000210313, ENST00000373904
Protein sequencees
Ensembl_PRO: ENSP00000210313, ENSP00000363011
RefSeq: NP_001257356.1, NP_005038.1
Others
UniRef100: UniRef100_Q16401
UniRef90: UniRef90_Q16401
UniRef50: UniRef50_Q16401
UniGene: Hs.193725
CCDS: CCDS59143.1, CCDS6824.1

全选

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研究热度

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