| Type | Description |
|---|---|
| Definition | cysteinyl leukotriene receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:41:00 | Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients. | 31614358 |
| 2020-08-01 13:05:00 | findings indicate that CysLT2R was involved in inflammation and neuronal damage by inducing the activation of microglia M1 polarization and NF-kappaB pathway, inhibiting microglia M1 polarization and promoting microglia polarization toward M2 phenotype which may exerts neuroprotective effects. | 31726033 |
| 2020-05-02 12:18:00 | Polymorphisms in the CYSLTR2 gene are associated with asthma, atopy markers and helminth infection in Brazilian individuals, which may lead to protection or risk for such conditions, however, more studies are needed to evaluate the functional of this variants here in described. | 31126515 |
| 2020-04-11 10:36:00 | CYSLTR2-mutant melanocytic blue neoplasms frequently exhibit a heavily pigmented exophytic tumor with a silhouette resembling "pigmented epithelioid melanocytoma" rather than usual cellular blue nevus. | 31162285 |
| 2018-12-01 11:54:00 | Its mutation is found in patients with meningeal melanocytic tumour. | 29476293 |
| Type | IDs |
|---|---|
| Synonymous | CYSLT2, CYSLT2R, GPCR21, HG57, HPN321, KPG_011, PSEC0146, hGPCR21 |
| Gene |
UniProtKB-ID:
CLTR2_HUMAN,
Q5KU17_HUMAN,
A4ZKH2_HUMAN
UniprotKB:
Q9NS75,
Q5KU17,
A4ZKH2
UniParc:
UPI0001502D46,
UPI000003BCCC
EMBL:
BC096832,
EF141525,
AB041644,
AF279611,
EF141530,
AY389504,
EF141524,
EF141526,
AY853711,
BC069160,
AB038269,
EF141527,
EF141529,
EF141528,
EF141523,
CH471075,
AL137118,
AK291739,
AB083603,
AB041947,
AF254664
Ensembl:
ENSG00000152207
KO:
hsa:57105
|
| Nucleutide sequences |
EMBL-CDS:
AAH69160.1,
BAB03601.1,
BAB89316.1,
AAK69485.1,
AAQ91330.1,
AAG17281.1,
BAB16379.1,
EAX08802.1,
AAW47925.1,
AAH96832.1,
BAF84428.1,
BAD83598.1,
ABO61879.1,
ABO61876.1,
ABO61880.1,
ABO61874.1,
ABO61877.1,
ABO61878.1,
ABO61881.1,
ABO61875.1
Gene_ORFName:
PSEC0146,
hCG_1647464
Ensembl_TRS:
ENST00000614739,
ENST00000282018
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000282018,
ENSP00000477930
RefSeq:
NP_001295397.1,
NP_001295399.1,
NP_001295396.1,
NP_065110.1,
NP_001373943.1,
NP_001295405.1,
NP_001373941.1,
NP_001373942.1,
NP_001295394.1,
NP_001295400.1,
NP_001295398.1
|
| Others |
UniRef100:
UniRef100_Q9NS75
UniRef90:
UniRef90_Q9NS75
UniRef50:
UniRef50_Q9NS75
UniGene:
Hs.253706,
Hs.614318
CCDS:
CCDS9412.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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