| Type | Description |
|---|---|
| Definition | TP53 induced glycolysis regulatory phosphatase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:55:00 | TIGAR impedes compression-induced intervertebral disc degeneration by suppressing nucleus pulposus cell apoptosis and autophagy. | 31317559 |
| 2020-08-13 18:50:00 | Down-regulation of TFAM increases the sensitivity of tumour cells to radiation via p53/TIGAR signalling pathway. | 31062473 |
| 2020-07-25 11:24:00 | TIGAR expression is modulated during pancreatic ductal adenocarcinoma development | 31983610 |
| 2020-06-06 12:24:00 | TIGAR promotes metabolic reprogramming and regulates NSC differentiation through an epigenetic mechanism. | 30814486 |
| 2020-05-30 13:00:00 | TIGAR protein, is present in SN Lewy bodies of both sporadic PD and DLB. The absence of TIGAR protein in the pathological inclusions of MND or MSA suggests disease specificity and further raises the possibility that TIGAR may be involved in PD pathogenesis. | 30267647 |
| Type | IDs |
|---|---|
| Synonymous | C12orf5, FR2BP |
| Gene |
UniProtKB-ID:
TIGAR_HUMAN
UniprotKB:
Q9NQ88
UniParc:
UPI000006DFEB
EMBL:
CH471116,
BC012340,
AY425618,
AJ272206,
AK313226
Ensembl:
ENSG00000078237
KO:
hsa:57103
|
| Nucleutide sequences |
EMBL-CDS:
EAW88849.1,
AAQ98969.1,
BAG36037.1,
AAH12340.1,
CAC01127.1
Ensembl_TRS:
ENST00000179259
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000179259
RefSeq:
NP_065108.1
|
| Others |
UniRef100:
UniRef100_Q9NQ88
UniRef90:
UniRef90_Q9NQ88
UniRef50:
UniRef50_Q9NQ88
UniGene:
Hs.504545
CCDS:
CCDS8525.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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