| Type | Description |
|---|---|
| Definition | Cas scaffold protein family member 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-13 11:16:00 | The results of this study showed that Cas scaffolding protein family member 4 with protein tyrosine kinase 2 and their significant role in the activation of downstream signaling pathways in Alzheimer's disease. | 29789968 |
| 2017-03-04 12:01:00 | High expression of CASS4 is associated with invasion in non-small cell lung cancer. | 27677288 |
| 2015-10-10 11:38:00 | EFS and CASS4 protein function in the context of the larger CAS family group. [Review] | 26119091 |
| 2013-03-30 13:09:00 | Hepl is overexpressed in the nucleus and aberrantly accumulates in the cytoplasm of non-small cell lung cancer cells, and Hepl may play a role in the progression of lung cancer, including lymph node metastasis and TNM stage. | 23001926 |
| 2010-01-21 00:00:00 | HEPL maintains Cas family function in localization to focal adhesions, as well as regulation of FAK activity, focal adhesion integrity, and cell spreading. | 18256281 |
| Type | IDs |
|---|---|
| Synonymous | C20orf32, CAS4, HEFL, HEPL |
| Gene |
UniProtKB-ID:
CASS4_HUMAN,
B4DII4_HUMAN
UniprotKB:
Q9NQ75,
B4DII4
UniParc:
UPI000002A749,
UPI00001285DB,
UPI00017A708D,
UPI000002A748
EMBL:
AK295613,
BC027951,
CH471077,
AK027760,
AJ276678,
AL121914
Ensembl:
ENSG00000087589
KO:
hsa:57091
|
| Nucleutide sequences |
EMBL-CDS:
EAW75547.1,
CAC00655.1,
AAH27951.1,
EAW75546.1,
BAB55351.1,
BAG58496.1
Ensembl_TRS:
ENST00000360314,
ENST00000434344
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000353462,
ENSP00000410027
RefSeq:
NP_065089.2,
NP_001157588.1,
NP_001157586.1,
NP_001157587.1,
XP_006723894.1
|
| Others |
UniRef100:
UniRef100_Q9NQ75,
UniRef100_B4DII4
UniRef90:
UniRef90_Q9NQ75
UniRef50:
UniRef50_Q9NQ75
UniGene:
Hs.473144
CCDS:
CCDS54475.1,
CCDS33492.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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