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5708 PSMD2

5708

PSMD2

proteasome 26S subunit, non-ATPase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition proteasome 26S subunit, non-ATPase 2

研究结论

Date Results Publications
2021-03-27 14:45:00 TRAF2 Knockdown in Nasopharyngeal Carcinoma Induced Arrest and Enhanced the Sensitivity to Radiotherapy. 32566659
2020-04-11 10:59:00 The authors demonstrate that PSMD1 and PSMD2 promote the proliferation of HepG2 cells via facilitating cellular lipid droplet accumulation. 31703613
2020-01-04 10:48:00 Asporin (ASPN) interacts with proteasome 26S subunit non-ATPase 2 (PSMD2) and promotes the proliferation of gastric cancer (GC) cells. 31136974
2019-08-10 12:16:00 Study found that PSMD2 was markedly upregulated in breast cancer. High PSMD2 expression was significantly correlated with poor prognosis. PSMD2 knockdown inhibited cell proliferation and arrested cell cycle at G0/G1 phase in vitro, as well as suppressed tumor growth in vivo. Mechanically, PSMD2 physically interacted with p21 and p27 and mediated their ubiquitin-proteasome degradation with the cooperation of USP14. 29777785
2019-03-09 10:19:00 By recruiting the 26S proteasome and the ubiquitin-selective ATPase p97 to arsenite-induced stress granules, ZFAND1 ensures their timely clearance and prevents their aberration. 29804830

名称对应

Type IDs
Synonymous P97, RPN1, S2, TRAP2
Gene
UniProtKB-ID: PSMD2_HUMAN
UniprotKB: Q13200
UniParc: UPI000013277E, UPI000198CB9C, UPI000198CB9B
EMBL: AK302177, D78151, AK301759, BC007897, X86446, BC002997, BT009736, AC078797, U12596, BC002368
Ensembl: ENSG00000175166
KO: hsa:5708
Nucleutide sequences
EMBL-CDS: BAG63219.1, AAH07897.1, AAH02368.1, CAA60167.1, AAA87705.1, BAG63543.1, AAP88738.1, AAH02997.1, BAA11226.1
Ensembl_TRS: ENST00000435761, ENST00000310118, ENST00000439383
Protein sequencees
Ensembl_PRO: ENSP00000402618, ENSP00000416028, ENSP00000310129
RefSeq: NP_002799.3, NP_001265637.1, NP_001265638.1
Others
UniRef100: UniRef100_Q13200
UniRef90: UniRef90_Q13200
UniRef50: UniRef50_Q13200
UniGene: Hs.518464
CCDS: CCDS63854.1, CCDS63853.1, CCDS3258.1

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