CHRNA10 - cholinergic receptor nicotinic alpha 10 subunit-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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57053 CHRNA10

基因描述

Type	Description
Definition	cholinergic receptor nicotinic alpha 10 subunit

研究结论

Date	Results	Publications
2020-12-19 13:43:00	Hair cell alpha9alpha10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products.	32929005
2012-11-24 10:13:00	A two order of magnitude species difference is reported in potency of alpha-conotoxin RgIA for rat versus human alpha9alpha10 nAChR.	22774872
2011-01-01 11:33:00	CHRNA10 may have a role in "dizziness" in response to tobacco	19760673
2010-12-05 22:08:00	Observational study of gene-disease association. (HuGE Navigator)	20734064
2010-09-15 22:06:00	Observational study of gene-disease association. (HuGE Navigator)	20584212

名称对应

Type	IDs
Gene	UniProtKB-ID: ACH10_HUMAN, C4IXS7_HUMAN UniprotKB: Q9GZZ6, C4IXS7 UniParc: UPI0000038CF1, UPI0001A33851 EMBL: BC136250, AF327367, AF199235, AJ295237, AJ278118 Ensembl: ENSG00000129749 KO: hsa:57053
Nucleutide sequences	EMBL-CDS: AAK14333.1, CAC16144.1, CAC20435.1, AAG00795.2, AAI36251.1 Ensembl_TRS: ENST00000250699
Protein sequencees	Ensembl_PRO: ENSP00000250699 RefSeq: NP_065135.2, NP_001289964.1, XP_011518536.1, NP_001289963.1
Others	UniRef100: UniRef100_C4IXS7, UniRef100_Q9GZZ6 UniRef90: UniRef90_C4IXS7, UniRef90_Q9GZZ6 UniRef50: UniRef50_G3X8Z7, UniRef50_Q9JLB5 UniGene: Hs.732806 CCDS: CCDS7745.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32929005	Hair cell Î±9Î±10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products. Proc Natl Acad Sci U S A Shenyan Gu , Daniel Knowland , Jose A Matta , Min L O'Carroll , Weston B Davini , Madhurima Dhara , Hae-Jin Kweon , David S Bredt	2020-09-29	-
22774872	Molecular basis for the differential sensitivity of rat and human Î±9Î±10 nAChRs to Î±-conotoxin RgIA. J. Neurochem. Layla Azam , J Michael McIntosh	2012-09-01	Chrna10, Chrna9, CHRNA9, CHRNA10
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20231857	Why do young women smoke? VI. A controlled study of nicotine effects on attention: pharmacogenetic interactions. Pharmacogenomics J. A Rigbi , A Yakir , K Sarner-Kanyas , Y Pollak , B Lerer	2011-02-01	CHRNA2, CHRNA4, CHRNA7, CHRNB2, CHRNB3, CHRNA10, CHRNA6
20734064	A large-scale candidate gene association study of age at menarche and age at natural menopause. Hum. Genet. Chunyan He , Peter Kraft , Daniel I Chasman , Julie E Buring , Constance Chen , Susan E Hankinson , Guillaume ParÃ© , Stephen Chanock , Paul M Ridker , David J Hunter	2010-11-01	PPIF, GDF11, FST, LEFTY1, SLC12A7, CGA, ADAMTS13, SLC2A6, CHRNA1, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA7, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG, CCR3, NLRP5, CNR1, PROKR2, ACVR1C, COMT, CRHR1, CRHR2, MAPK14, EME1, GDF7, SLC2A12, ADRB2, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, GRK3, CYP3A4, CYP11A1, CYP17A1, CYP19A1, DBH, ACE, CITED4, DDC, AKR1C2, DIAPH2, DRD1, DRD2, DRD3, DRD5, AGT, ECT2, EML1, AKT1, ESR1, ESR2, F2, F5, ALDH1B1, FGFR1, FMO1, FMO3, FMR1, AFF2, LEPROTL1, FSHB, FSHR, ANKK1, PCSK9, GABRB2, GALT, FGFR1OP2, GDF1, GDF2, MSTN, GDF9, GDF10, AMH, GH1, GHR, GHRH, AMHR2, GHRHR, BMP10, GNB3, GNRH1, GNRHR, MCHR1, NR3C1, HBE1, HIVEP1, AIRE, HSD3B1, HSD3B2, HSD17B1
20584212	Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. Genes Brain Behav. N L Saccone , T-H Schwantes-An , J C Wang , R A Grucza , N Breslau , D Hatsukami , E O Johnson , J P Rice , A M Goate , L J Bierut	2010-10-01	-
20379614	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Mol. Med. Jed E Rose , FrÃ©dÃ©rique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl	2010-03-17	-
19760673	Association of CHRN genes with "dizziness" to tobacco. Am J Med Genet B Neuropsychiatr Genet Marissa A Ehringer , Matthew B McQueen , Nicole R Hoft , Nancy L Saccone , Jerry A Stitzel , Jen C Wang , Laura J Bierut	2010-03-05	-
19156168	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Eur. J. Hum. Genet. Anna C Need , Richard S E Keefe , Dongliang Ge , Iris Grossman , Sam Dickson , Joseph P McEvoy , David B Goldstein	2009-07-01	-
19259974	Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. Am J Med Genet B Neuropsychiatr Genet Nancy L Saccone , Scott F Saccone , Anthony L Hinrichs , Jerry A Stitzel , Weimin Duan , Michele L Pergadia , Arpana Agrawal , Naomi Breslau , Richard A Grucza , Dorothy Hatsukami , Eric O Johnson , Pamela A F Madden , Gary E Swan , Jen C Wang , Alison M Goate , John P Rice , Laura J Bierut	2009-06-05	-

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