| Type | Description |
|---|---|
| Definition | gap junction protein, alpha 5b |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:37:00 | in zebrafish, Cx39.4 expression in melanophores is required but expression in xanthophores is not necessary for stripe patterning, whereas Cx41.8 expression in xanthophores is sufficient for the patterning, and Cx41.8 expression in melanophores might stabilize the stripes | 31666235 |
| 2016-06-04 10:14:00 | Data (including data from studies in transgenic zebrafish) suggest gap junctions formed by Cx41.8 play important role in stripe/spot patterning; mutations in Cx41.8 effect patterning by reduced function (I203F) or dominant negative effects (M7). | 26598520 |
| 2015-09-12 10:07:00 | Gap junctions composed of connexins 41.8 and 39.4 are essential for colour pattern formation in zebrafish. | 25535837 |
| 2012-09-01 11:02:00 | Connexin41.8 regulates skin pattern variation. | 22313791 |
| 2010-01-21 00:00:00 | Patch-clamp experiments of connexin hemichannels demonstrated that the I202F substitution in allele leo(tq270) disrupted the channel function of connexin41.8. These results demonstrate that these mutations lead to a variety of leopard spot patterns. | 16845369 |
| Type | IDs |
|---|---|
| Synonymous | cx41.8 |
| Gene |
UniProtKB-ID:
Q3S2N4_DANRE
UniprotKB:
Q3S2N4
UniParc:
UPI00001A1B12
EMBL:
DQ177156
KO:
dre:570445
|
| Nucleutide sequences |
EMBL-CDS:
ABA02517.1
|
| Protein sequencees |
RefSeq:
NP_001030160.1
|
| Others |
UniRef100:
UniRef100_Q3S2N4
UniRef90:
UniRef90_B3DID2
UniRef50:
UniRef50_B3DID2
UniGene:
Dr.135739
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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