| Type | Description |
|---|---|
| Definition | solute carrier family 17 member 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 11:52:00 | In mammals, VGLUT1 gained a proline-rich sequence that recruits endophilinA1 and turns the transporter into a regulator of synaptic vesicles organization and spontaneous release. | 31663854 |
| 2019-06-08 12:11:00 | The findings of this study indicate that Slc17A7 located on 1p/19q may simultaneously influence tumor development. | 29890994 |
| 2018-01-13 12:02:00 | Study revealed susceptibility of glutamatergic nerve terminals to Abeta induced toxicity and underlined the importance of VGLUT1 in the progression of Alzheimer's disease, as the decrease of this protein levels could increase the susceptibility to subsequent deleterious inputs by exacerbating Abeta induced neuroinflammation and synaptic plasticity disruption. | 27258819 |
| 2018-01-13 11:20:00 | This study was the first to demonstrate an association between genetic polymorphism at rs7417284 SNP in the promoter region of the SLC17A7 gene and concussion severity and duration. Based upon these findings, rs74174284 is a potential predictive genetic marker for identifying athletes who are more susceptible for altered recovery times and worse motor speed ImPACT scores after sport-related concussion. | 27029226 |
| 2016-12-17 10:16:00 | Results suggest that activation of JNK in Alzheimer's disease (AD) inhibits insulin signaling which could lead to a decreased expression of VGLUT1, therefore contributing to the glutamatergic deficit in AD | 26836159 |
| Type | IDs |
|---|---|
| Synonymous | BNPI, VGLUT1 |
| Gene |
UniProtKB-ID:
VGLU1_HUMAN
UniprotKB:
Q9P2U7
UniParc:
UPI0000E04A9A,
UPI00017A6F8E,
UPI000006F6B8
EMBL:
AK294226,
AK294405,
BC059379,
CH471177,
AB032436,
AC010619
Ensembl:
ENSG00000104888
KO:
hsa:57030
|
| Nucleutide sequences |
EMBL-CDS:
BAA92875.1,
EAW52485.1,
AAH59379.1,
BAG57657.1,
BAG57530.1
Ensembl_TRS:
ENST00000221485,
ENST00000600601
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000221485,
ENSP00000470338
RefSeq:
NP_064705.1
|
| Others |
UniRef100:
UniRef100_Q9P2U7
UniRef90:
UniRef90_Q3TXX4
UniRef50:
UniRef50_Q3TXX4
UniGene:
Hs.375616
CCDS:
CCDS12764.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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