| Type | Description |
|---|---|
| Definition | ADAM metallopeptidase domain 17 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 10:19:00 | The inhibition of pathway and over-activation of ERK1/2 might be associated with the beneficial role of rutaecarpine in hypertensive cardiac hypertrophy, thus providing additional evidence for preventing hypertensive cardiac hypertrophy with rutaecarpine. | 30953402 |
| 2019-03-30 10:07:00 | Nox1/4 dual inhibitor GKT137831 protects against hypertensive cardiac remodelling in AAC-induced hypertensive rats, and the inhibition of ADAM17-dependent proinflammatory cytokines-induced signalling pathways. | 30551445 |
| 2018-12-29 10:18:00 | CGRP has an anti-inflammatory effect in vascular smooth muscle cells (VSMCs) stimulated by Ang II; ADAM17 is involved in the protective effect of CGRP against Ang II-induced inflammation via the EGFR-ERK1/2 pathway in VSMCs | 30046277 |
| 2017-02-04 10:12:00 | Enhanced ADAM17 expression, along with decreased TIMP-3 and increased TNF-alpha expression, especially within one week after acute myocardial infarction | 26944439 |
| 2015-11-21 10:27:00 | high glucose-induced HIF-1alpha activation and ADAM17 up-regulation. | 26175156 |
| Type | IDs |
|---|---|
| Synonymous | TACE |
| Gene |
UniProtKB-ID:
ADA17_RAT
UniprotKB:
Q9Z1K9
UniParc:
UPI00001254D6
EMBL:
AJ012603
KO:
rno:57027
|
| Nucleutide sequences |
EMBL-CDS:
CAA10072.1
|
| Protein sequencees |
RefSeq:
NP_064702.1
|
| Others |
UniRef100:
UniRef100_Q9Z1K9
UniRef90:
UniRef90_P78536
UniRef50:
UniRef50_P78536
UniGene:
Rn.144585
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员