| Type | Description |
|---|---|
| Definition | pyridoxal phosphatase |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 12:16:00 | In non-adherent glioblastoma cell lines cultured in serum-free medium, chronophin knockdown induces phenotypic changes, e.g. in colony formation and transcription, but these are highly dependent on the cellular background. CIN knockdown in the glioblastoma cell lines NCH421k and NCH644 increased active vitamin B6 levels. | 29724193 |
| 2016-01-16 10:28:00 | Chronophin has a role in coordinating cell leading edge dynamics by controlling active cofilin levels | 26324884 |
| 2013-07-27 10:52:00 | Splicing of SH3BP1 and CIN gene loci produces the novel brain specific splice variant BGIN. | 23223568 |
| 2010-01-21 00:00:00 | We report the biochemical isolation of chronophin (CIN), a unique cofilin-activating phosphatase of the haloacid dehalogenase (HAD) superfamily and an important novel regulator of cofilin-mediated actin reorganization. | 15580268 |
| 2010-01-21 00:00:00 | Results suggest that the transduction of the PEP-1-PLPP fusion protein can be one mode of PLP level regulation, and to replenish this enzyme in the various neurological disorders related to vitamin B(6). | 18510874 |
| Type | IDs |
|---|---|
| Synonymous | CIN, PLP, dJ37E16.5 |
| Gene |
UniProtKB-ID:
PLPP_HUMAN,
A0A024R1I3_HUMAN
UniprotKB:
Q96GD0,
A0A024R1I3
UniParc:
UPI000006D362
EMBL:
BC064922,
Z83844,
CH471095,
HM005576,
BC000320,
BC009756,
AY125047
Ensembl:
ENSG00000241360
KO:
hsa:57026
|
| Nucleutide sequences |
EMBL-CDS:
AAH00320.1,
AAH09756.2,
AAM94358.1,
AAH64922.1,
AEE61173.1,
EAW60176.1,
EAW60177.1
Gene_ORFName:
hCG_41847
Ensembl_TRS:
ENST00000215904
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000215904
RefSeq:
NP_064711.1
|
| Others |
UniRef100:
UniRef100_Q96GD0
UniRef90:
UniRef90_Q96GD0
UniRef50:
UniRef50_Q96GD0
UniGene:
Hs.632762
CCDS:
CCDS13953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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