| Type | Description |
|---|---|
| Definition | laminin, alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-28 10:41:00 | Through deletion analyses, the study established that lama1 expression in the anterior CNS and paraxial mesoderm is driven by an enhancer located within intron 1. Also, endogenous lama1 expression driven by the intronic enhancer is controlled by Hedgehog signaling, possibly through Gli/Zic binding sites within the lama1 intron 1 enhancer, in the paraxial mesoderm. | 27856309 |
| 2017-06-03 12:13:00 | Loss of lama1 leads to divergent effects on focal adhesion assembly in a spatiotemporally-specific manner. Laminin is required for multiple steps of optic cup morphogenesis, including optic stalk constriction, invagination, and formation of a spherical lens. In lama1(UW1) mutants, loss of epithelial polarity and altered adhesion lead to defective tissue architecture and formation of a disorganized retina. | 27339294 |
| 2010-01-21 00:00:00 | tag1, lama1 and vangl2 participate in a common mechanism that integrates signaling between the FBMN and its environment to regulate migration. | 19013446 |
| 2010-01-21 00:00:00 | Analysis of zebrafish laminin-alpha 1 mutants reveals multiple functions for laminin-alpha 1 in the outgrowth and guidance of central nervous system axons | 16261616 |
| 2010-01-21 00:00:00 | The phenotypic and genetic analyses of a recessive, larval lethal zebrafish mutant, bal(a69), characterized by severe eye defects and shortened body axis, is reported. | 16973147 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q45H72_DANRE
UniprotKB:
Q45H72
UniParc:
UPI0000576491
EMBL:
DQ131910
KO:
dre:569971
|
| Nucleutide sequences |
EMBL-CDS:
AAZ30636.1
|
| Protein sequencees |
RefSeq:
NP_001030158.1
|
| Others |
UniRef100:
UniRef100_Q45H72
UniRef90:
UniRef90_A0A0R4II20
UniRef50:
UniRef50_P19137
UniGene:
Dr.94156
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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