| Type | Description |
|---|---|
| Definition | translocase of outer mitochondrial membrane 22 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-13 22:24:00 | A directed proteomic approach discovered the novel interaction of BKCa with Tom22, a component of the mitochondrion outer membrane import system, and the adenine nucleotide translocator (ANT). | 27592226 |
| 2016-07-30 11:19:00 | Tom22 is essential for metabolic conversion, as its knockdown by small interfering RNA (siRNA) completely ablated progesterone conversion in both steroidogenic mouse Leydig MA-10 and human adrenal NCI cells. | 26787839 |
| 2014-06-21 13:04:00 | Blockade of mitochondrial protein import triggers the recruitment of PARK2, by PINK1, to the TOMM machinery. | 24149440 |
| 2012-06-30 11:18:00 | Studies indicate that PUMA and TOMM22 as potential targets for miRNA-BART viral transcripts. | 22178394 |
| 2012-03-10 10:25:00 | The interaction with the cytosolic domain of Tom22 helps Bax to acquire a conformation able to interact with the outer mitochondrial membrane. | 22198199 |
| Type | IDs |
|---|---|
| Synonymous | 1C9-2, MST065, MSTP065, TOM22 |
| Gene |
UniProtKB-ID:
TOM22_HUMAN,
Q549C5_HUMAN
UniprotKB:
Q9NS69,
Q549C5
UniParc:
UPI0000040C1F
EMBL:
AK312076,
AF163256,
AB040119,
CH471095,
AK024731,
BC009363,
CR456475,
AB041906
Ensembl:
ENSG00000100216
KO:
hsa:56993
|
| Nucleutide sequences |
EMBL-CDS:
AAH09363.1,
BAB14979.1,
BAB03306.1,
CAG30361.1,
BAB16408.1,
BAG35012.1,
EAW60257.1,
EAW60253.1,
AAQ13585.1
Gene_ORFName:
hCG_2010808
Ensembl_TRS:
ENST00000216034
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216034
RefSeq:
NP_064628.1
|
| Others |
UniRef100:
UniRef100_Q9NS69
UniRef90:
UniRef90_Q9NS69
UniRef50:
UniRef50_Q9NS69
UniGene:
Hs.595072
CCDS:
CCDS13975.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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