| Type | Description |
|---|---|
| Definition | PR/SET domain 9 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:55:00 | ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair. | 32744506 |
| 2019-08-24 11:26:00 | Recent findings have highlighted an unexpected molecular control of the distribution of meiotic double-strand breaks (DSBs) in mammals by a rapidly evolving gene in trans, PR-domain-containing 9 (PRDM9), and specific DNA sequence motifs in cis | 30311566 |
| 2019-02-16 12:24:00 | PRDM9 expression in tumors is significantly higher than in healthy neighboring tissues. Aberrant expression of PRDM9 is associated with genomic instability in cancers. | 30341163 |
| 2019-01-19 11:04:00 | PRDM9 activity leads to the erosion of its own binding sites and the rapid evolution of its DNA-binding domain. PRDM9 may also contribute to reproductive isolation, as it is involved in hybrid sterility potentially due to a reduction of its activity in specific heterozygous contexts. [Review] | 30161134 |
| 2019-01-05 12:36:00 | PRDM9 influences the possibility of genetic exchange by determining the locations of meiotic recombination hotspots in most mammals. (Review) | 29366606 |
| Type | IDs |
|---|---|
| Synonymous | KMT8B, MEISETZ, MSBP3, PFM6, ZNF899 |
| Gene |
UniProtKB-ID:
PRDM9_HUMAN
UniprotKB:
Q9NQV7
UniParc:
UPI00006C9E90
EMBL:
AC025451,
AF275816,
AK301776,
DQ388610
Ensembl:
ENSG00000164256
KO:
hsa:56979
|
| Nucleutide sequences |
EMBL-CDS:
ABD47939.1,
AAF87242.1,
BAG63234.1
Ensembl_TRS:
ENST00000296682
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296682
RefSeq:
NP_001297143.1,
NP_001363829.1,
NP_064612.2
|
| Others |
UniRef100:
UniRef100_Q9NQV7
UniRef90:
UniRef90_Q9NQV7
UniRef50:
UniRef50_Q96EQ9
UniGene:
Hs.283096
CCDS:
CCDS43307.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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