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56970 ATXN7L3

56970

ATXN7L3

ataxin 7 like 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition ataxin 7 like 3

研究结论

Date Results Publications
2020-12-05 12:57:00 Long non-coding RNA DSCAM-AS1 contributes to the tumorigenesis of cervical cancer by targeting miR-877-5p/ATXN7L3 axis. 31737900
2017-08-19 11:00:00 ATXN7L3 and ENY2 orchestrate activities of multiple deubiquitinating enzymes, including USP27x and USP51, and that imbalances in these activities likely potentiate human diseases including cancer. 27132940
2011-10-29 10:21:00 Downregulation of ATXN7L3 by short hairpin RNA speci fi cally inactivated the SAGA deubiquitination activity, leading to a strong increase of global H2B ubiquitination and a moderate increase of H2A ubiquitination. 21746879
2010-10-30 11:01:00 The solution structures of the SCA7 domain of both ATXN7 and ATXN7L3 reveal a new, common zinc-finger motif at the heart of two distinct folds, providing a molecular basis for the observed functional differences. 20634802
2010-01-21 00:00:00 ATXN7L3, USP22, & ENY2 are required cofactors for full transcriptional activity by nuclear receptors. The deubiquitinase activity of TFTC/STAGA HAT counteracts heterochromatin silencing & is a positive cofactor for in vivo nuclear receptor activation. 18206972

名称对应

Type IDs
Gene
UniProtKB-ID: AT7L3_HUMAN
UniprotKB: Q14CW9
UniParc: UPI00001613AC, UPI0000DA6BB8
EMBL: BC113595, BC037418, BC126113, AL390158, AK056002
Ensembl: ENSG00000087152
Nucleutide sequences
EMBL-CDS: AAH37418.1, BAB71070.1, AAI26114.1, CAB99093.1, AAI13596.1
Ensembl_TRS: ENST00000389384, ENST00000454077
Protein sequencees
Ensembl_PRO: ENSP00000374035, ENSP00000397259
RefSeq: NP_001369243.1, NP_001369244.1, NP_001369240.1, NP_001369245.1, NP_001369241.1, NP_001369238.1, NP_001369239.1, NP_001369242.1, NP_001369237.1
Others
UniRef100: UniRef100_Q14CW9
UniRef90: UniRef90_Q14CW9
UniRef50: UniRef50_Q14CW9
UniGene: Hs.512651
CCDS: CCDS42345.1, CCDS45697.1

全选

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