| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase 10 |
| Date | Results | Publications |
|---|---|---|
| 2017-04-29 11:08:00 | Significantly, we show that introduction of mapk10 mutations into ret heterozygotes enhanced the ENS deficit, supporting MAPK10 as a Hirschsprung disease (HSCR) susceptibility locus. Our studies demonstrate that ret heterozygous zebrafish is a sensitized model, with many significant advantages over existing murine models, to explore the pathophysiology and complex genetics of HSCR. | 27902697 |
| Type | IDs |
|---|---|
| Synonymous | zgc:123234 |
| Gene |
UniProtKB-ID:
A4QP40_DANRE,
A0A0R4I9H8_DANRE,
Q32LV0_DANRE,
A0A0R4IB91_DANRE,
A0A0R4IKK9_DANRE
UniprotKB:
A4QP40,
A0A0R4I9H8,
Q32LV0,
A0A0R4IB91,
A0A0R4IKK9
UniParc:
UPI0000F70635,
UPI0001F79F83,
UPI00005E2523,
UPI0007382279,
UPI0001F79F82
EMBL:
CR678270,
CR354555,
BC139642,
BC109420
Ensembl:
ENSDARG00000102730
KO:
dre:569698
|
| Nucleutide sequences |
EMBL-CDS:
AAI39643.1,
AAI09421.1
Ensembl_TRS:
ENSDART00000159899,
ENSDART00000161753,
ENSDART00000162834,
ENSDART00000161289,
ENSDART00000160711
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000133641,
ENSDARP00000129891,
ENSDARP00000139912,
ENSDARP00000131673,
ENSDARP00000134326
RefSeq:
XP_021324567.1,
XP_017208306.1,
NP_001032790.1,
XP_005161531.1,
XP_017208303.1,
XP_021324568.1,
XP_017208304.1,
NP_001305248.1,
XP_009293442.1,
NP_001305247.1,
XP_017208305.1,
XP_005161528.1,
NP_001305250.1,
XP_005161530.1,
XP_009293445.1
|
| Others |
UniRef100:
UniRef100_A4QP40,
UniRef100_A0A0R4I9H8,
UniRef100_A0A0R4IB91,
UniRef100_A0A0R4IKK9
UniRef90:
UniRef90_A4QP40,
UniRef90_A0A0R4I9H8,
UniRef90_A0A0R4IB91,
UniRef90_P53779-2
UniRef50:
UniRef50_A4QP40,
UniRef50_F7GE32,
UniRef50_Q91Y86,
UniRef50_P53779-2
UniGene:
Dr.119966
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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