| Type | Description |
|---|---|
| Definition | matrix extracellular phosphoglycoprotein |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:19:00 | MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk. | 33097703 |
| 2020-02-15 10:16:00 | sequencing identified a rare segregating heterozygous frameshift variant p.(Gln425Lysfs*38) in MEPE. We performed variant burden and variance components analyses in a large otosclerosis cohort and demonstrated that nonsense and frameshift MEPE variants were significantly enriched in affected subjects (p = 0.0006-0.0060). | 30287925 |
| 2014-05-17 12:12:00 | Results indicate an association of MEPE gene inactivation with decreased survival after DNA damage. | 23570370 |
| 2014-03-27 11:07:00 | Mice deficient in an ortholog of MEPE show increased bone mass and are resistant to aging-related bone loss. | 12421822 |
| 2012-07-21 10:43:00 | results indicated that MEPE appeared to play an important positive role in proliferation and osteogenesis differentiation of DPCs through interaction with downstream signals. | 22341070 |
| Type | IDs |
|---|---|
| Synonymous | OF45 |
| Gene |
UniProtKB-ID:
MEPE_HUMAN,
Q8NC19_HUMAN,
A0A024RDD1_HUMAN
UniprotKB:
Q9NQ76,
Q8NC19,
A0A024RDD1
UniParc:
UPI0001D27F85,
UPI000003B034,
UPI0000071B80,
UPI0000E5AC25
EMBL:
BC128158,
AC093768,
AK075076,
CH471057,
AF325916,
AJ276396,
DQ854717
Ensembl:
ENSG00000152595
KO:
hsa:56955
|
| Nucleutide sequences |
EMBL-CDS:
CAB97250.1,
EAX06002.1,
EAX06001.1,
AAK70343.1,
ABI64294.1,
AAI28159.1,
BAC11386.1,
EAX06003.1
Gene_ORFName:
hCG_38545
Ensembl_TRS:
ENST00000361056,
ENST00000560249,
ENST00000540395,
ENST00000395102,
ENST00000424957
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000453994,
ENSP00000354341,
ENSP00000378534,
ENSP00000416984,
ENSP00000443491
RefSeq:
NP_001171625.1,
NP_001171623.1,
NP_001278112.1,
NP_064588.1,
NP_001171624.1,
NP_001171626.1
|
| Others |
UniRef100:
UniRef100_Q8NC19,
UniRef100_Q9NQ76
UniRef90:
UniRef90_Q8NC19,
UniRef90_Q9NQ76
UniRef50:
UniRef50_A0A2I3LUK4,
UniRef50_Q9NQ76
UniGene:
Hs.676357
CCDS:
CCDS77940.1,
CCDS54776.1,
CCDS3625.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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