| Type | Description |
|---|---|
| Definition | nitrilase family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:09:00 | NIT2 overexpression predicts poor prognosis in tongue squamous cell carcinoma patients. | 31925645 |
| 2015-12-19 12:03:00 | Downregulation of NIT2 inhibits colon cancer cell proliferation and induces cell cycle arrest through the caspase-3 and pathways | 25738796 |
| 2015-10-31 11:19:00 | Human NIT1/2 are not involved in the metabolism of vildagliptin. | 25008847 |
| 2012-10-13 11:21:00 | The activity and substrate specificity of human Nit2 was determined with alpha-ketoglutaramate and succinamate as substrates. | 22674578 |
| 2010-01-21 00:00:00 | Genotype analysis in 4 types of tumor tissue showed allelic imbalance surrounding NIT2 locus; results show that NIT2 plays an important role in cell growth inhibition & links to malignancies, suggesting Nit2 may be a potential tumor suppressor candidate | 17488281 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-8a |
| Gene |
UniProtKB-ID:
NIT2_HUMAN,
V9HW91_HUMAN
UniprotKB:
Q9NQR4,
V9HW91
UniParc:
UPI000004A5A7
EMBL:
BC107890,
AF284574,
CH471052,
BC020620,
AK313704,
AF260334,
FJ224326
Ensembl:
ENSG00000114021
KO:
hsa:56954
|
| Nucleutide sequences |
EMBL-CDS:
AAF87103.1,
BAG36450.1,
AAI07891.1,
EAW79825.1,
AAH20620.1,
EAW79824.1,
AAG44665.1,
ACI46018.1
Gene_ORFName:
CUA002
Ensembl_TRS:
ENST00000394140
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377696
RefSeq:
NP_064587.1
|
| Others |
UniRef100:
UniRef100_Q9NQR4
UniRef90:
UniRef90_Q9NQR4
UniRef50:
UniRef50_Q9NQR4
UniGene:
Hs.439152
CCDS:
CCDS33806.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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