| Type | Description |
|---|---|
| Definition | 5',3'-nucleotidase, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2015-09-26 10:25:00 | An alternative splice variant of the mdN gene containing an 18-nucleotide insertion encoding 6 amino acids (GKWPAT) at the 3'-end of the penultimate exon 4 has been characterized. | 24506201 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2010-01-21 00:00:00 | structures of dNT-2 in complex with bound phosphate and beryllium trifluoride plus thymidine as model for a phosphoenzyme-product complex | 12352955 |
| 2010-01-21 00:00:00 | Overproduction in cultured cells and functional aspects | 12124385 |
| 2010-01-21 00:00:00 | substrate specificity analysis of the human mitochondrial deoxyribonucleotidase | 16004879 |
| Type | IDs |
|---|---|
| Synonymous | dNT-2, dNT2, mdN |
| Gene |
UniProtKB-ID:
NT5M_HUMAN,
Q2I378_HUMAN
UniprotKB:
Q9NPB1,
Q2I378
UniParc:
UPI000013C515,
UPI0000073CAE
EMBL:
DQ323995,
BC035838,
AF210652,
AJ277557,
AC006071
Ensembl:
ENSG00000205309
KO:
hsa:56953
|
| Nucleutide sequences |
EMBL-CDS:
CAB99251.1,
AAH35838.1,
AAF87076.1,
ABC88597.1
Ensembl_TRS:
ENST00000389022,
ENST00000616989
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000373674,
ENSP00000481269
RefSeq:
XP_016880368.1,
XP_011522267.1,
XP_005256794.1,
XP_005256789.1,
XP_011522266.1,
XP_005256788.1,
NP_064586.1,
XP_011522265.1,
XP_005256791.1,
XP_005256790.1,
XP_011522268.1,
XP_011522269.1,
XP_011522264.1
|
| Others |
UniRef100:
UniRef100_Q2I378,
UniRef100_Q9NPB1
UniRef90:
UniRef90_Q9NPB1
UniRef50:
UniRef50_Q9NPB1
UniGene:
Hs.513977
CCDS:
CCDS32581.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28319085 |
Nat. Biotechnol. Kyuho Han , Edwin E Jeng , Gaelen T Hess , David W Morgens , Amy Li , Michael C Bassik |
2017-05-01 | - |
| 24506201 |
J Enzyme Inhib Med Chem Petr Pachl , Milan Fábry , Václav Veverka , JiÅà Brynda , PavlÃna ÅezáÄová |
2015-02-01 |
NT5M
|
| 24104479 |
Mol. Syst. Biol. Franco J Vizeacoumar , Roland Arnold , Frederick S Vizeacoumar , Megha Chandrashekhar , Alla Buzina , Jordan T F Young , Julian H M Kwan , Azin Sayad , Patricia Mero , Steffen Lawo , Hiromasa Tanaka , Kevin R Brown , Anastasia Baryshnikova , Anthony B Mak , Yaroslav Fedyshyn , Yadong Wang , Glauber C Brito , Dahlia Kasimer , Taras Makhnevych , Troy Ketela , Alessandro Datti , Mohan Babu , Andrew Emili , Laurence Pelletier , Jeff Wrana , Zev Wainberg , Philip M Kim , Robert Rottapel , Catherine A O'Brien , Brenda Andrews , Charles Boone , Jason Moffat |
2013-01-01 |
ADAM10,
RAMP1,
BCAS2,
ANAPC10,
CEBPD,
CCT7,
YME1L1,
KDM5B,
TBC1D8,
TREX2,
CREBBP,
ZNF358,
SREK1,
C12orf66,
CSNK2B,
CDC42EP5,
KIAA2026,
COCH,
DHFR,
CYB5R3,
RILPL2,
EME2,
ELK4,
STK32A,
ENO2,
SLC36A1,
FANCD2,
VWCE,
ALDH3B1,
ATXN7L1,
ICK,
SNW1,
SNRNP200,
AKR1B1,
RFTN1,
SLC9A8,
PIGN,
KPNA6,
OSBP2,
MMS22L,
PRPF31,
FBXL6,
BLOC1S1,
PLEK2,
POLM,
GPER1,
C16orf72,
GTPBP8,
SLC25A6,
ZBTB48,
XIAP,
ST8SIA6,
ZNF181,
IDH2,
KRAS,
HES5,
LLGL2,
LTA4H,
LTK,
MXD1,
MBP,
MDFI,
DNAJB9,
MTNR1A,
NAB1,
NONO,
NOTCH1,
NUMA1,
NUP98,
OPRL1,
PBX3,
TXNDC11,
NDUFA13,
TFB1M,
RNFT1,
POLR3K,
LUC7L3,
FXYD1,
POLD2,
POLR2L,
POU3F3,
INO80,
SAMD4B,
HES6,
TTC27,
CDC37L1,
CDK5RAP2,
KMT2E,
NXT2,
MAP2K1,
B2M,
PSMA3,
PSMB2,
DUS3L,
ARNTL2,
NT5M,
PSMD1,
PTEN,
CWC22
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20877624 |
Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. PLoS One Sher L Hendrickson , James A Lautenberger , Leslie Wei Chinn , Michael Malasky , Efe Sezgin , Lawrence A Kingsley , James J Goedert , Gregory D Kirk , Edward D Gomperts , Susan P Buchbinder , Jennifer L Troyer , Stephen J O'Brien |
2010-09-21 | - |
| 16004879 |
Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase. Structure Karin Walldén , Benedetta Ruzzenente , Agnes Rinaldo-Matthis , Vera Bianchi , Pär Nordlund |
2005-07-01 | - |
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 12352955 |
Crystal structure of a human mitochondrial deoxyribonucleotidase. Nat. Struct. Biol. Agnes Rinaldo-Matthis , Chiara Rampazzo , Peter Reichard , Vera Bianchi , Pär Nordlund |
2002-10-01 | - |
| 12124385 |
J Biol Chem Lisa Gallinaro , Katia Crovatto , Chiara Rampazzo , Giovanna Pontarin , Paola Ferraro , Eva Milanesi , Peter Reichard , Vera Bianchi |
2002-09-20 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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