| Type | Description |
|---|---|
| Definition | XPA binding protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:30:00 | Data suggest that XPA-binding protein 2 (XAB2) serves as a guardian of RNA polymerase II subunit A (POLR2A) expression to ensure global gene expression and antagonize cell senescence. | 31216022 |
| 2017-08-05 11:01:00 | these results support a novel function of XAB2 in mitotic cell cycle regulation, which is partially mediated by transcription regulation on CENPE. | 27735937 |
| 2017-06-24 11:39:00 | we suggest that the XAB2 complex mediates DNA damage response events important for the end resection step of homologous recombination , and speculate that its adjacent-localization relative to double-strand break marked by gH2AX is important for this function | 27084940 |
| 2016-05-14 10:47:00 | Study identifies XAB2 tagSNPs (rs794078 and rs4134816) significantly associated with the risk of non-small cell lung cancer (NSCLC) in Chinese population, which supports XAB2 playing significant role in the development of NSCLC. | 26228655 |
| 2015-10-03 11:19:00 | Results of protein-protein interaction between human Dbr1 and factors found in the Intron Large complex identify Xab2 and a novel protein CWF19L1 as specific interactors of DBR1. | 25671812 |
| Type | IDs |
|---|---|
| Synonymous | HCNP, HCRN, NTC90, SYF1 |
| Gene |
UniProtKB-ID:
SYF1_HUMAN
UniprotKB:
Q9HCS7
UniParc:
UPI0000001BDE
EMBL:
AB033003,
BC008778,
AF258567,
AF226051,
AF547265,
AK074035,
BC007208,
AB026111
Ensembl:
ENSG00000076924
KO:
hsa:56949
|
| Nucleutide sequences |
EMBL-CDS:
AAF86951.1,
AAH08778.1,
BAB84861.1,
AAN17847.1,
AAH07208.1,
BAA86491.1,
AAG23770.1,
BAB15807.1
Gene_ORFName:
PP3898
Ensembl_TRS:
ENST00000358368
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000351137
RefSeq:
NP_064581.2
|
| Others |
UniRef100:
UniRef100_Q9HCS7
UniRef90:
UniRef90_Q9HCS7
UniRef50:
UniRef50_Q9HCS7
UniGene:
Hs.9822
CCDS:
CCDS32892.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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