| Type | Description |
|---|---|
| Definition | chromodomain helicase DNA binding protein 7 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-28 11:54:00 | chd7 may control the expression of sema3E to regulate cranial neural crest cell migration | 31464029 |
| 2019-04-20 12:14:00 | chd7 was critical for thymic development and T-lymphopenia in CHARGE syndrome may be mainly attributed to the defects of thymic organogenesis. | 29353058 |
| 2019-04-06 10:16:00 | The conserved genetics and transparency of the zebrafish have provided new insights into the consequences of chd7 gene dysfunction on the GI system and cranial nerve patterning. These findings highlight the opportunity of the zebrafish to serve as a preclinical model for studying compounds that may improve GI motility in individuals with CHARGE syndrome. | 29660852 |
| 2017-07-15 10:48:00 | Our zebrafish CHARGE model thus reveals important regulatory roles for Chd7 at multiple points of neural crest development viz., migration, fate choice and differentiation and we suggest that sox10 deregulation is an important driver of the neural crest-derived aspects of Chd7 dependent CHARGE syndrome. | 27418670 |
| 2013-11-30 11:56:00 | knockdown of the jumonji domain-containing histone demethylase fbxl10/kdm2bb, a repressor of ribosomal RNA genes, rescues cell proliferation and cartilage defects in chd7 morphant embryos and can lead to complete rescue of the CHARGE syndrome phenotype. | 23920116 |
| Type | IDs |
|---|---|
| Synonymous | si:ch211-197o6.2, wu:cegs2051, wu:fb37f10, wu:fb39h04, wu:fd19h06 |
| Gene |
UniProtKB-ID:
F1QGL1_DANRE
UniprotKB:
F1QGL1
UniParc:
UPI0001E92704
EMBL:
CR450710
Ensembl:
ENSDARG00000075211
KO:
dre:569471
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000135230
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000114372
RefSeq:
XP_697956.4
|
| Others |
UniRef100:
UniRef100_F1QGL1
UniRef90:
UniRef90_F1QGL1
UniRef50:
UniRef50_F1QGL1
UniGene:
Dr.33371,
Dr.116391,
Dr.159483,
Dr.159570
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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