| Type | Description |
|---|---|
| Definition | mitochondrial fission factor |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:08:00 | Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation. | 32224193 |
| 2020-09-12 16:02:00 | Mcl-1 inhibits Mff-mediated mitochondrial fragmentation and apoptosis. | 31941601 |
| 2020-06-13 11:22:00 | We found that the receptors mitochondrial fission factor (Mff) and mitochondrial elongation factor 1/2 (MIEF1/2) interact with and recruit Drp1(pS637) to mitochondria and that elevated Mff or MIEF levels promote Drp1(pS637) accumulation on mitochondria. We also noted that protein kinase A which mediates phosphorylation of Drp1 on Ser-637, is partially present on mitochondria and interacts with both MIEFs and Mff | 31533986 |
| 2020-05-30 11:32:00 | Study demonstrated that protein isoforms of mitochondrial fission factor (MFF1 and MFF2) were overexpressed in patients with non-small cell lung cancer and formed homo- and heterodimeric complexes with the voltage-dependent anion channel-1 (VDAC1), a key regulator of mitochondrial outer membrane permeability. | 31582380 |
| 2020-01-25 14:06:00 | finding strategies to regulate the balance of the DUSP1-JNK-Mff signaling pathway and mitochondrial homeostasis may be a therapeutic target for treating diabetic nephropathy in clinical practice. | 30191967 |
| Type | IDs |
|---|---|
| Synonymous | C2orf33, EMPF2, GL004 |
| Gene |
UniProtKB-ID:
MFF_HUMAN,
A1MAC2_HUMAN,
A0A0A0MS29_HUMAN
UniprotKB:
Q9GZY8,
A1MAC2,
A0A0A0MS29
UniParc:
UPI0002B8AC93,
UPI00000720C1,
UPI00004F9C4A,
UPI000006DC40,
UPI0000073FDC,
UPI0000072C36
EMBL:
BC000797,
CH471063,
AF246239,
AC097662,
BC093024,
AF258660,
AK026137,
AF226049,
AL833032
Ensembl:
ENSG00000168958
KO:
hsa:56947
|
| Nucleutide sequences |
EMBL-CDS:
AAF86949.1,
AAG44658.1,
BAB15373.1,
AAG44486.1,
AAH00797.1,
AAY24252.1,
CAH56328.1,
AAH93024.1,
EAW70868.1,
EAW70859.1
Gene_ORFName:
AD033,
AD030,
GL004,
hCG_2013339
Ensembl_TRS:
ENST00000337110,
ENST00000354503,
ENST00000353339,
ENST00000349901,
ENST00000409616,
ENST00000304593,
ENST00000409565,
ENST00000392059
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304898,
ENSP00000338412,
ENSP00000304134,
ENSP00000346498,
ENSP00000302037,
ENSP00000386964,
ENSP00000386641,
ENSP00000375912
RefSeq:
XP_016860001.1,
XP_016860003.1,
XP_016860004.1,
NP_001263997.1,
NP_064579.3,
XP_024308776.1,
XP_005246742.1,
NP_001263990.1,
XP_024308777.1,
NP_001263994.1,
XP_011509803.1,
XP_005246744.1,
XP_011509802.1,
NP_001263996.1,
NP_001263991.1,
XP_005246738.1,
XP_005246740.1,
XP_006712700.1,
NP_001263992.1,
XP_006712702.1,
XP_016860002.1,
XP_005246739.1,
XP_005246741.1,
XP_005246743.1,
NP_001263995.1,
NP_001263993.1,
XP_005246745.1,
XP_006712701.1
|
| Others |
UniRef100:
UniRef100_A0A0A0MS29,
UniRef100_Q9GZY8
UniRef90:
UniRef90_Q9GZY8,
UniRef90_A0A0A0MS29
UniRef50:
UniRef50_Q9GZY8,
UniRef50_Q9GZY8-5
UniGene:
Hs.471528
CCDS:
CCDS63140.1,
CCDS63142.1,
CCDS63141.1,
CCDS63139.1,
CCDS2465.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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