| Type | Description |
|---|---|
| Definition | 5-hydroxymethylcytosine binding, ES cell specific |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Structural biology of DNA abasic site protection by SRAP proteins. | 32663791 |
| 2020-02-29 10:40:00 | This study reports crystal structures of the human HMCES SOS response-associated peptidase (SRAP) domain in complex with DNA-damage substrates, including HMCES cross-linked with an abasic site within a 3' overhang DNA. | 31235913 |
| 2016-04-30 10:49:00 | The findings of this study described in this study emphasise the importance of 5hmC in brain development and ageing and will help to better understand the complexity and plasticity of the brain. | 25471351 |
| 2015-12-19 11:03:00 | 5-hmC might be involved in the pathogenesis of Nonalcoholic Fatty Liver Disease by regulating liver mitochondrial biogenesis and PPARGC1A expression. | 26356709 |
| 2015-12-05 10:44:00 | The expression of 5-hmC was an independent prognostic factor for overall survival of EOC [epithelial ovarian canc] patients. | 25827305 |
| Type | IDs |
|---|---|
| Synonymous | C3orf37, DC12, SRAPD1 |
| Gene |
UniProtKB-ID:
HMCES_HUMAN
UniprotKB:
Q96FZ2
UniParc:
UPI000006FF4D
EMBL:
AC137695,
BC088363,
BC009993,
BC050686,
AF201934,
CH471052,
BC010125
Ensembl:
ENSG00000183624
KO:
hsa:56941
|
| Nucleutide sequences |
EMBL-CDS:
AAH88363.1,
EAW79266.1,
AAF86870.1,
AAH10125.1,
AAH50686.1,
AAH09993.1
Ensembl_TRS:
ENST00000383463,
ENST00000389735,
ENST00000502878
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000374385,
ENSP00000426215,
ENSP00000372955
RefSeq:
NP_001357273.1,
NP_001357272.1,
NP_064572.2,
NP_001006109.1,
NP_001350810.1,
NP_001357274.1
|
| Others |
UniRef100:
UniRef100_Q96FZ2
UniRef90:
UniRef90_Q96FZ2
UniRef50:
UniRef50_Q96FZ2
UniGene:
Hs.458320
CCDS:
CCDS33852.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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