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56919 DHX33

56919

DHX33

DEAH-box helicase 33

protein-coding

Homo sapiens

基因描述

Type Description
Definition DEAH-box helicase 33

研究结论

Date Results Publications
2020-08-22 15:26:00 DHX33 Recruits Gadd45a To Cause DNA Demethylation and Regulates a Subset of Gene Transcription. 32312884
2020-04-11 12:37:00 This study highlights that DHX33 protein is critical in glioblastoma cell proliferation and its potential as a novel therapeutic drug target. 30552990
2020-03-14 12:18:00 DHX33 is highly expressed in human colon cancers. DHX33 and Wnt/beta-catenin reciprocally regulate each other. 32004669
2020-02-05 12:29:00 Results reveal that DHX33 represses apoptosis through the direct upregulation of Bcl-2 gene transcription. AP-2beta is a binding partner for DHX33 and that DHX33 acts as a coactivator for AP-2beta to promote the transcription of antiapoptotic Bcl-2 gene. 31182639
2018-11-10 11:19:00 DHX33 doublet is due to alternative translation initiation by two in-frame initiation codons. DHX33 translation initiation from either AUG codon happens at equal efficiency. Short DHX33 protein has similar cellular location and functions with full-length DHX33. Leaky scanning normally occurs in DHX33 mRNA translation, which may serve as a safeguard mechanism to ensure optimal DHX33 translation efficiency. 29864424

名称对应

Type IDs
Synonymous DDX33
Gene
UniProtKB-ID: DHX33_HUMAN, B4DIS6_HUMAN
UniprotKB: Q9H6R0, B4DIS6
UniParc: UPI000013C861, UPI00017A7220, UPI00005E2727
EMBL: CH471108, CR936655, AK295074, BC030017, AK295760, AK025625, AC004148, AK026944
Ensembl: ENSG00000005100
KO: hsa:56919
Nucleutide sequences
EMBL-CDS: BAB15596.1, CAI56793.1, AAH30017.1, BAB15193.1, BAG58120.1, EAW90332.1, BAG58588.1
Ensembl_TRS: ENST00000225296
Protein sequencees
Ensembl_PRO: ENSP00000225296
RefSeq: NP_001186628.1, NP_064547.2, XP_016880366.1
Others
UniRef100: UniRef100_Q9H6R0, UniRef100_B4DIS6
UniRef90: UniRef90_Q9H6R0
UniRef50: UniRef50_Q9H6R0
UniGene: Hs.250456
CCDS: CCDS11072.1

全选

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