| Type | Description |
|---|---|
| Definition | spire type actin nucleation factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-12 11:47:00 | interferes with bacterial binding in Salmonella typhimurium host cell invasion | 27627128 |
| 2016-07-16 10:35:00 | Data suggest formin homology domain (FH2) of Fmn2 binds actin at filament barbed end as weak capper and plays a role in displacing WASP homology domain 2 (WH2) domains of Spire-1 from actin; competitive binding of Fmn2 vs Spire-1 aids actin assembly. | 26668326 |
| 2016-07-02 11:29:00 | This DNA damage-induced nuclear actin assembly requires two biologically and physically linked nucleation factors: Formin-2 and Spire-1/Spire-2. | 26287480 |
| 2016-06-28 11:26:00 | The authors propose Spire1C isoform cooperates with INF2 to regulate actin assembly at endoplasmic reticulum-mitochondrial contacts. | 26305500 |
| 2014-10-18 13:35:00 | Spire recruits Fmn2 and facilitates its association with actin filaments barbed ends. | 24586110 |
| Type | IDs |
|---|---|
| Synonymous | Spir-1 |
| Gene |
UniProtKB-ID:
SPIR1_HUMAN
UniprotKB:
Q08AE8
UniParc:
UPI000022A698,
UPI000040B71C,
UPI00001C1FFE,
UPI000176ADB9,
UPI000006F793
EMBL:
AP005482,
BC125207,
CH471113,
AP001028,
AL833817,
BC125206,
AK290180,
AB032961,
BC115005,
AP001029,
AJ277587
Ensembl:
ENSG00000134278
KO:
hsa:56907
|
| Nucleutide sequences |
EMBL-CDS:
AAI15006.1,
AAI25208.1,
BAF82869.1,
AAI25207.1,
BAA86449.2,
CAD38680.1,
EAX01546.1,
CAB96370.1
Ensembl_TRS:
ENST00000410092,
ENST00000453447,
ENST00000440472,
ENST00000409402
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000387266,
ENSP00000387226,
ENSP00000407050,
ENSP00000404752
RefSeq:
NP_064533.3,
XP_011524003.1,
XP_005258179.1,
XP_011524005.1,
NP_001122098.1,
XP_024306992.1,
NP_001122099.1,
XP_024306993.1,
XP_011524004.1
|
| Others |
UniRef100:
UniRef100_Q08AE8
UniRef90:
UniRef90_Q08AE8
UniRef50:
UniRef50_Q08AE8
UniGene:
Hs.515283
CCDS:
CCDS45830.1,
CCDS32790.2,
CCDS45829.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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