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56904 SH3GLB2

56904

SH3GLB2

SH3 domain containing GRB2 like, endophilin B2

protein-coding

Homo sapiens

基因描述

Type Description
Definition SH3 domain containing GRB2 like, endophilin B2

研究结论

Date Results Publications
2018-01-27 11:50:00 Here the authors report that Endophilin B2, similarly to Endophilin B1, plays an indispensable role in mitochondria sequestration and inner mitochondrial membrane (IMM) protein degradation during mitophagy. 27112121
2017-07-08 12:40:00 Data (including data from studies in knockout mice) suggest that SH3GLB2 regulates trafficking of endocytic vesicles and autophagosomes to late endosomes or lysosomes; despite having an intracellular localization and tissue distribution similar to endophilin B1, endophilin B2 is dispensable for mitochondrial apoptosis. 28455444
2013-11-30 10:37:00 the potential importance of the endophilin B2-plectin complex in the biological functions depending on nuclear migration and positioning. 23921385
2010-06-30 22:06:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614
2010-01-21 00:00:00 identified a nonmutated HLA-A2-binding epitope in the human ortholog SH3GLB2, which primed T cells from healthy HLA-A2(+) individuals 18303116

名称对应

Type IDs
Synonymous PP6569, PP9455, RRIG1
Gene
UniProtKB-ID: SHLB2_HUMAN, A0A024R896_HUMAN, B7ZC38_HUMAN
UniprotKB: Q9NR46, A0A024R896, B7ZC38
UniParc: UPI000004A0D5, UPI000036768C, UPI000006D1AE
EMBL: AF257319, CH471090, AL592211, AB058751, AF258589, BC014635
Ensembl: ENSG00000148341
KO: hsa:56904
Nucleutide sequences
EMBL-CDS: AAH14635.1, AAG23792.1, BAB47477.2, AAF81226.1, EAW87855.1, EAW87854.1, EAW87858.1, EAW87857.1
Gene_ORFName: PP578, hCG_30604
Ensembl_TRS: ENST00000372564, ENST00000372559, ENST00000372554, ENST00000417224
Protein sequencees
Ensembl_PRO: ENSP00000361645, ENSP00000361640, ENSP00000361634, ENSP00000402566
RefSeq: NP_001356842.1, XP_006717254.1, XP_006717252.1, XP_006717253.1, NP_001273975.1, XP_006717251.1, NP_001356843.1, XP_005252155.1, NP_064530.1, XP_005252158.1, NP_001273974.1, NP_001356844.1
Others
UniRef100: UniRef100_B7ZC38, UniRef100_Q9NR46
UniRef90: UniRef90_B7ZC38, UniRef90_Q9NR46
UniRef50: UniRef50_Q9NR46
UniGene: Hs.460238
CCDS: CCDS6916.1, CCDS69680.1

全选

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