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56901 NDUFA4L2

56901

NDUFA4L2

NDUFA4 mitochondrial complex associated like 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition NDUFA4 mitochondrial complex associated like 2

研究结论

Date Results Publications
2021-01-16 15:56:00 Evaluating the clinical significance of SHMT2 and its co-expressed gene in human kidney cancer. 33066813
2020-03-28 10:39:00 Study showed that mitochondrial NDUFA4L2 was overexpressed in non-small cell lung cancer (NSCLC) tumor tissues. NDUFA4L2 was also overexpressed in NSCLC cell lines cultured in hypoxic conditions. Its expression is regulated by HIF1A. 30710412
2019-12-21 11:00:00 This study identified NDUFA4L2 as the most highly expressed gene in renal cancer cells and evaluated its role in sustaining angiogenesis, chemoresistance, and mitochondrial dysfunction. 30538212
2019-01-19 12:07:00 hypoxia promotes the viability of cardiac stem cells in serum-free medium by HIF-1alpha/NDUFA4L2 signaling pathway. 29953852
2018-02-03 11:07:00 This study has provided the first clinical relevance of NDUFA4L2 in human cancer, and since NDUFA4L2 was HIF1-regulated in Hepatocellular carcinoma cells, suggested that Hepatocellular carcinoma patients with NDUFA4L2 overexpression may be suitable candidates for HIF inhibitor treatment. 26819450

名称对应

Type IDs
Synonymous NUOMS
Gene
UniProtKB-ID: NUA4L_HUMAN, A0A024RB39_HUMAN
UniprotKB: Q9NRX3, A0A024RB39
UniParc: UPI0000130A2A
EMBL: AF164796, CH471054, BC011910, CR457176
Ensembl: ENSG00000185633
KO: hsa:56901
Nucleutide sequences
EMBL-CDS: CAG33457.1, AAH11910.1, AAF80760.1, EAW97003.1, EAW97002.1
Gene_ORFName: hCG_41236
Ensembl_TRS: ENST00000554503, ENST00000393825
Protein sequencees
Ensembl_PRO: ENSP00000377411, ENSP00000450664
RefSeq: NP_064527.1
Others
UniRef100: UniRef100_Q9NRX3
UniRef90: UniRef90_Q9NRX3
UniRef50: UniRef50_Q9NRX3
UniGene: Hs.75069
CCDS: CCDS8935.1

全选

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