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56897 WRNIP1

56897

WRNIP1

Werner helicase interacting protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition Werner helicase interacting protein 1

研究结论

Date Results Publications
2020-09-12 16:00:00 miR-22 enhances the radiosensitivity of small-cell lung cancer by targeting the WRNIP1. 31190355
2019-09-28 11:09:00 The WRNIP1-mediated reduction in the amount of PrimPol was suppressed by treatment of the cells with proteasome inhibitors, suggesting that WRNIP1 is involved in the degradation of PrimPol via the proteasome. 31061318
2017-10-28 11:00:00 findings define the WHIP-TRIM14-PPP6C mitochondrial signalosome required for RIG-I-mediated innate antiviral immunity. 29053956
2017-09-02 10:58:00 WRNIP1 connects PCNA monoubiquitination with ATMIN/ATM to activate ATM signalling in response to replication stress and contribute to the maintenance of genomic stability. 26549024
2017-07-01 10:06:00 The authors show that WRNIP1 is directly involved in preventing uncontrolled MRE11-mediated degradation of stalled replication forks by promoting RAD51 stabilization on ssDNA. 27242363

名称对应

Type IDs
Synonymous WHIP, bA420G6.2
Gene
UniProtKB-ID: WRIP1_HUMAN
UniprotKB: Q96S55
UniParc: UPI000007036A, UPI000006D3BD, UPI000004A506, UPI000045885D
EMBL: AL139092, AK026179, AK223593, AK315471, AF218313, CH471087, AB209723, BC018923, AB056152
Ensembl: ENSG00000124535
KO: hsa:56897
Nucleutide sequences
EMBL-CDS: AAF80563.1, BAD92960.1, EAW55087.1, BAB15383.1, BAD97313.1, AAH18923.1, BAB60709.1, BAG37857.1
Ensembl_TRS: ENST00000380764, ENST00000380771, ENST00000618555, ENST00000380773, ENST00000380769
Protein sequencees
Ensembl_PRO: ENSP00000370146, ENSP00000477551, ENSP00000370150, ENSP00000370148, ENSP00000370141
RefSeq: NP_064520.2, XP_016866549.1, NP_569079.1, XP_005249289.1
Others
UniRef100: UniRef100_Q96S55
UniRef90: UniRef90_Q96S55
UniRef50: UniRef50_Q96S55
UniGene: Hs.236828
CCDS: CCDS4475.1, CCDS4476.1

全选

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