| Type | Description |
|---|---|
| Definition | UDP-glucose glycoprotein glucosyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:34:00 | Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2. | 33320095 |
| 2021-01-09 13:32:00 | Glycan dependent refolding activity of ER glucosyltransferase (UGGT). | 32858085 |
| 2018-02-17 11:27:00 | The authors identify an interaction between TAPBPR and UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1), a folding sensor in the calnexin/calreticulin quality control cycle that is known to regenerate the Glc1Man9GlcNAc2 moiety on glycoproteins. The results suggest the formation of a multimeric complex, dependent on a conserved cysteine at position 94 in TAPBPR, in which TAPBPR promotes the association of UGT1 with p | 28425917 |
| 2018-01-06 11:10:00 | In this study, we aimed to clarify the contribution of the noncatalytic domains by comparing activities of truncated forms of recombinant HUGT1/HUGT2 and HUGT1/HUGT2 chimeras with full-length enzymes. | 27496766 |
| 2017-11-04 12:04:00 | both vIL-6 and VKORC1v2 interact with calnexin cycle proteins UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1), which catalyzes monoglucosylation of N-glycans, and oppositely acting glucosidase II (GlucII), and that vIL-6 can promote protein folding. | 28878084 |
| Type | IDs |
|---|---|
| Synonymous | HUGT1, UGCGL1, UGT1 |
| Gene |
UniProtKB-ID:
UGGG1_HUMAN
UniprotKB:
Q9NYU2
UniParc:
UPI000007456E,
UPI00000707D8
EMBL:
AC108059,
AF227905,
BC041098,
AK023671,
AC017079
Ensembl:
ENSG00000136731
KO:
hsa:56886
|
| Nucleutide sequences |
EMBL-CDS:
BAB14632.1,
AAY14885.1,
AAH41098.1,
AAY14735.1,
AAF66232.1
Ensembl_TRS:
ENST00000259253
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000259253
RefSeq:
XP_006712698.1,
XP_016859997.1,
XP_006712697.1,
XP_016859996.1,
XP_006712699.1,
NP_064505.1,
XP_016859999.1,
XP_016859998.1
|
| Others |
UniRef100:
UniRef100_Q9NYU2
UniRef90:
UniRef90_Q9NYU2
UniRef50:
UniRef50_Q9NYU2
UniGene:
Hs.743306
CCDS:
CCDS2154.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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