| Type | Description |
|---|---|
| Definition | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:08:00 | NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release. | 32155413 |
| 2016-08-13 11:27:00 | BDNF application can rescue the morphological deficits in hippocampal pyramidal neurons devoid of Jacob. Taken together, the data suggest that the absence of Jacob in early development interrupts a positive feedback loop between BDNF signaling | 26977770 |
| 2016-03-05 10:32:00 | NELF knockout is associated with impaired pubertal development and subfertility. | 25731822 |
| 2015-02-07 10:13:00 | Findings strongly indicate that NELF is part of the PPARalpha-mediated transcription regulatory network that maintains metabolic homeostasis in cardiomyocytes. | 24656816 |
| 2014-11-29 10:41:00 | Jacob operates as a mobile hub that docks NMDA receptor-derived signalosomes to nuclear target sites. | 24317321 |
| Type | IDs |
|---|---|
| Synonymous | Jacob, Nelf |
| Gene |
UniProtKB-ID:
NSMF_MOUSE,
Q3TY90_MOUSE,
A2AJ95_MOUSE,
Q3TNG2_MOUSE,
A2AJ96_MOUSE,
A2AJ92_MOUSE
UniprotKB:
Q99NF2,
Q3TY90,
A2AJ95,
Q3TNG2,
A2AJ96,
A2AJ92
UniParc:
UPI000002825B,
UPI0000D776B4,
UPI0000025C1D,
UPI0000551C90,
UPI00005B2139,
UPI0000020F88,
UPI0000D776B1,
UPI0000028091,
UPI00000E9703,
UPI00005AD230
EMBL:
AK158803,
AK041478,
AK004986,
AK045384,
AK019560,
AJ278902,
AK053402,
AL732585,
AK165300,
BC006642,
AF266508
Ensembl:
ENSMUSG00000006476
KO:
mmu:56876
|
| Nucleutide sequences |
EMBL-CDS:
BAC35375.1,
AAH06642.1,
BAC30955.1,
CAC27332.1,
AAF74501.2,
BAC32338.1,
BAB23721.1,
BAC25597.1,
BAE34673.1,
BAE38127.1
Ensembl_TRS:
ENSMUST00000100334,
ENSMUST00000102931,
ENSMUST00000006646,
ENSMUST00000114386,
ENSMUST00000114388,
ENSMUST00000074422
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000097908,
ENSMUSP00000006646,
ENSMUSP00000099995,
ENSMUSP00000110028,
ENSMUSP00000110030,
ENSMUSP00000074022
RefSeq:
XP_006498263.1,
NP_001171125.1,
XP_030107765.1,
XP_030107766.1,
XP_006498266.1,
XP_006498265.1,
XP_030107764.1,
NP_001034475.1,
NP_001171126.1,
NP_001034476.1,
NP_064672.2,
XP_006498264.1,
XP_030107763.1
|
| Others |
UniRef100:
UniRef100_A2AJ92,
UniRef100_A2AJ95,
UniRef100_Q3TY90,
UniRef100_Q3TNG2,
UniRef100_Q99NF2,
UniRef100_A2AJ96
UniRef90:
UniRef90_Q9EPI6,
UniRef90_Q9EPI6-2,
UniRef90_Q99NF2-2,
UniRef90_A2AJ92
UniRef50:
UniRef50_Q6X4W1,
UniRef50_Q9EPI6,
UniRef50_Q9EPI6-2
UniGene:
Mm.42956
CCDS:
CCDS15746.1,
CCDS15745.1,
CCDS15747.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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