| Type | Description |
|---|---|
| Definition | proteasome subunit alpha 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 12:05:00 | Genome-wide CRISPR screen followed by multiple siRNA screens in several pancreatic ductal adenocarcinoma (PDAC) cell models and in a noncancerous cell model validated PSMA6 as gene essential for cancer cells survival and showed that inhibition of this gene induces apoptosis and results in significantly reduced cell viability. Study provide compelling evidence that PSMA6 plays a significant oncogenic role. | 30898113 |
| 2019-05-18 11:41:00 | PSMA6 is post-transcriptionally repressed by the microRNA-4490 in diabetic nephropathy. | 30287505 |
| 2017-09-30 10:33:00 | Results suggest that proteasome subunit alpha type 6 (PSMA6) serves as an attractive target with a high therapeutic index for lung cancer. | 28165654 |
| 2017-07-01 12:19:00 | The 5' untranslated region of PSMA6 gene contains a single nucleotide polymorphism -8 C/G associated with End-stage kidney disease and might be a protective factor for the disease. | 27671905 |
| 2016-12-24 11:14:00 | These data indicate that hepatic expression of PSMA6, which is upregulated during viral hepatitis, likely depends on TLR3 activation and, that PSMA6 affects the expression of immunoregulatory ISG15, a proviral factor in the pathogenesis of hepatitis C virus infection. | 26833585 |
| Type | IDs |
|---|---|
| Synonymous | IOTA, PROS27, p27K |
| Gene |
UniProtKB-ID:
PSA6_HUMAN,
A0A140VK44_HUMAN
UniprotKB:
P60900,
A0A140VK44
UniParc:
UPI00017A77FE,
UPI00001FD3F4,
UPI0000001C1E
EMBL:
CH471078,
CR456944,
AK316223,
BC002979,
BC017882,
AK302008,
AL121594,
X59417,
AK313011,
X61972,
BC070137,
AK298920,
AL133163,
BC022354,
BC023659,
HM005584
Ensembl:
ENSG00000100902
KO:
hsa:5687
|
| Nucleutide sequences |
EMBL-CDS:
BAG63411.1,
AAH17882.1,
EAW65877.1,
BAG61026.1,
BAG35846.1,
AAH22354.1,
EAW65876.1,
CAA43964.1,
CAA42052.1,
AAH02979.1,
AAH23659.1,
CAG33225.1,
AAH70137.1,
BAH14594.1,
AEE61181.1
Ensembl_TRS:
ENST00000555764,
ENST00000622405,
ENST00000540871,
ENST00000261479
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000452566,
ENSP00000479620,
ENSP00000444844,
ENSP00000261479
RefSeq:
NP_001269163.1,
NP_002782.1,
NP_001269162.1,
NP_001269161.1,
XP_016876957.1
|
| Others |
UniRef100:
UniRef100_P60900
UniRef90:
UniRef90_P60900
UniRef50:
UniRef50_P60900
UniGene:
Hs.446260
CCDS:
CCDS61437.1,
CCDS9655.1,
CCDS61438.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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