Type | Description |
---|---|
Definition | insulinoma-associated 2 |
Date | Results | Publications |
---|---|---|
2019-07-13 12:21:00 | Insm2 is important in glucose-stimulated insulin secretion. | 30359270 |
2012-12-22 10:09:00 | Data suggest that IA-2 and IA-2beta play important roles in regulation of circadian rhythms, likely through their participation in neurochemical communication among neurons of suprachiasmatic nucleus. | 22785238 |
2011-07-23 10:25:00 | Results suggest that Insm2 plays an important role in the differentiation cascade of Ngn3/NeuroD1 signaling in pancreatic islets. | 21343251 |
Type | IDs |
---|---|
Synonymous | Mlt1 |
Gene |
UniProtKB-ID:
INSM2_MOUSE
UniprotKB:
Q9JMC2
UniParc:
UPI000024E89E
EMBL:
AB032418,
AC158398
Ensembl:
ENSMUSG00000045440
KO:
mmu:56856
|
Nucleutide sequences |
EMBL-CDS:
BAA92776.1
Ensembl_TRS:
ENSMUST00000051857
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000061046
RefSeq:
NP_064683.2
|
Others |
UniRef100:
UniRef100_Q9JMC2
UniRef90:
UniRef90_Q9JMC2
UniRef50:
UniRef50_Q9JMC2
UniGene:
Mm.114886
CCDS:
CCDS25919.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
30305733 |
Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature Teerawat Wiwatpanit , Sarah M Lorenzen , Jorge A Cantú , Chuan Zhi Foo , Ann K Hogan , Freddie Márquez , John C Clancy , Matthew J Schipma , Mary Ann Cheatham , Anne Duggan , Jaime GarcÃa-Añoveros |
2018-11-01 | - |
30359270 |
Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance. J Transl Med Lin Wang , Zhong Sheng Sun , Bingwu Xiang , Chi-Ju Wei , Yan Wang , Kevin Sun , Guanjie Chen , Michael S Lan , Gilberto N Carmona , Abner L Notkins , Tao Cai |
2018-10-25 | - |
22785238 |
Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β. Am. J. Physiol. Endocrinol. Metab. Sohan Punia , Kyle K Rumery , Elizabeth A Yu , Christopher M Lambert , Abner L Notkins , David R Weaver |
2012-09-15 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21343251 |
Endocrinology Tao Cai , Xiang Chen , Rennian Wang , Huan Xu , Yuhui You , Tao Zhang , Michael S Lan , Abner L Notkins |
2011-05-01 |
Neurog3,
Neurod1,
Insm2,
INSM2
|
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
20059953 |
Dev Cell Shigetoshi Yokoyama , Yoshiaki Ito , Hiroe Ueno-Kudoh , Hirohito Shimizu , Kenta Uchibe , Sonia Albini , Kazuhiko Mitsuoka , Shigeru Miyaki , Minako Kiso , Akane Nagai , Tomohiro Hikata , Tadahiro Osada , Noritsugu Fukuda , Satoshi Yamashita , Daisuke Harada , Valeria Mezzano , Masataka Kasai , Pier Lorenzo Puri , Yoshihide Hayashizaki , Haruo Okado , Megumi Hashimoto , Hiroshi Asahara |
2009-12-01 | - |
16602821 |
PLoS Biol Susan Magdaleno , Patricia Jensen , Craig L Brumwell , Anna Seal , Karen Lehman , Andrew Asbury , Tony Cheung , Tommie Cornelius , Diana M Batten , Christopher Eden , Shannon M Norland , Dennis S Rice , Nilesh Dosooye , Sundeep Shakya , Perdeep Mehta , Tom Curran |
2006-04-01 | - |
15618518 |
Mouse brain organization revealed through direct genome-scale TF expression analysis. Science Paul A Gray , Hui Fu , Ping Luo , Qing Zhao , Jing Yu , Annette Ferrari , Toyoaki Tenzen , Dong-In Yuk , Eric F Tsung , Zhaohui Cai , John A Alberta , Le-Ping Cheng , Yang Liu , Jan M Stenman , M Todd Valerius , Nathan Billings , Haesun A Kim , Michael E Greenberg , Andrew P McMahon , David H Rowitch , Charles D Stiles , Qiufu Ma |
2004-12-24 |
Zkscan16,
9130023H24Rik,
Srcap,
Zbtb48,
Akna,
Zfp729b,
Pds5b,
Dcun1d4,
Zfp513,
Zfp282,
Zfp956,
Trim68,
Champ1,
Zdhhc7,
Hinfp,
Zc3h10,
Zfp692,
Hoxb2,
Etv5,
Kdm3a,
Zfp120,
Zfp119a,
Isl2,
Barhl2,
Rcor2,
Rhox9,
E2f4,
Cbll1,
Rnf44,
Brd9,
Mbnl2,
Cphx1,
Tigd5,
Sharpin,
Prickle1,
Dhx57,
Tcf19,
Hmgxb3,
Otub1,
Lpxn,
Gbf1,
Atf5,
Ovol2,
Osr2,
Prrxl1,
Bmyc,
Jmjd6,
Whsc1,
Gcm2,
Chd4,
U2af1,
Foxp1,
Rnf187,
Zdhhc15,
Jmjd1c,
Ibtk,
Zzz3,
E2f8,
Sp110,
Uhrf2,
Rlf,
Rnf20,
Tbx10,
Lmo1,
Hoxc11,
Braf,
Mzf1,
Zfp91,
Zbtb25,
Dek,
Hivep1,
Prdm2,
Lmx1a,
Cse1l,
Nr3c2,
Tshz1,
Foxe1,
Lims1,
D17H6S56E-5,
Egln1,
C030039L03Rik,
2610305D13Rik,
Vmn1r50,
Foxp2,
Macf1,
Zbtb21,
Crip3,
Prdm15,
Brdt,
Ferd3l,
Vsx1,
Dcun1d1,
Adnp,
Aebp2,
Nr0b1,
Ahr,
Ahrr,
Aip,
Aire
|
12466851 |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature Y Okazaki , M Furuno , T Kasukawa , J Adachi , H Bono , S Kondo , I Nikaido , N Osato , R Saito , H Suzuki , I Yamanaka , H Kiyosawa , K Yagi , Y Tomaru , Y Hasegawa , A Nogami , C Schönbach , T Gojobori , R Baldarelli , D P Hill , C Bult , D A Hume , J Quackenbush , L M Schriml , A Kanapin , H Matsuda , S Batalov , K W Beisel , J A Blake , D Bradt , V Brusic , C Chothia , L E Corbani , S Cousins , E Dalla , T A Dragani , C F Fletcher , A Forrest , K S Frazer , T Gaasterland , M Gariboldi , C Gissi , A Godzik , J Gough , S Grimmond , S Gustincich , N Hirokawa , I J Jackson , E D Jarvis , A Kanai , H Kawaji , Y Kawasawa , R M Kedzierski , B L King , A Konagaya , I V Kurochkin , Y Lee , B Lenhard , P A Lyons , D R Maglott , L Maltais , L Marchionni , L McKenzie , H Miki , T Nagashima , K Numata , T Okido , W J Pavan , G Pertea , G Pesole , N Petrovsky , R Pillai , J U Pontius , D Qi , S Ramachandran , T Ravasi , J C Reed , D J Reed , J Reid , B Z Ring , M Ringwald , A Sandelin , C Schneider , C A M Semple , M Setou , K Shimada , R Sultana , Y Takenaka , M S Taylor , R D Teasdale , M Tomita , R Verardo , L Wagner , C Wahlestedt , Y Wang , Y Watanabe , C Wells , L G Wilming , A Wynshaw-Boris , M Yanagisawa , I Yang , L Yang , Z Yuan , M Zavolan , Y Zhu , A Zimmer , P Carninci , N Hayatsu , T Hirozane-Kishikawa , H Konno , M Nakamura , N Sakazume , K Sato , T Shiraki , K Waki , J Kawai , K Aizawa , T Arakawa , S Fukuda , A Hara , W Hashizume , K Imotani , Y Ishii , M Itoh , I Kagawa , A Miyazaki , K Sakai , D Sasaki , K Shibata , A Shinagawa , A Yasunishi , M Yoshino , R Waterston , E S Lander , J Rogers , E Birney , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group Phase I & II Team |
2002-12-05 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
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---|---|---|
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