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56848 SPHK2

56848

SPHK2

sphingosine kinase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition sphingosine kinase 2

研究结论

Date Results Publications
2021-03-06 13:24:00 Sphingosine kinase-2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl-1. 32124438
2020-07-18 11:31:00 Sphingosine kinase 1 and sphingosine kinase 2 have opposing roles in regulating p53-dependent function. siRNA knockdown of SK-2 reduces the expression of the pro-survival XBP-1s. 31954175
2020-05-23 11:51:00 Serum S1P is decreased in PACI, which may be partly due to downregulation of pancreatic SPHK2 31157539
2020-05-16 12:18:00 These findings suggested that LINC00460 could function as a competing endogenous RNA to regulate SphK2 expression by sponging miR-613 in papillary thyroid carcinoma. 30478856
2020-05-16 10:08:00 Increased SPHK2 levels in proliferating airway smooth muscle cells could be exploited to counteract airway smooth muscle thickening with synthetic substrates. 31247144

名称对应

Type IDs
Synonymous SK 2, SK-2, SPK 2, SPK-2
Gene
UniProtKB-ID: SPHK2_HUMAN, E9PCV4_HUMAN, A0A024QZH5_HUMAN, B3KV83_HUMAN
UniprotKB: Q9NRA0, E9PCV4, A0A024QZH5, B3KV83
UniParc: UPI0000202813, UPI000002B422, UPI00005A7A44, UPI0000E8A85A, UPI000002B423, UPI0000135E14, UPI0000E04A3E
EMBL: CH471177, AK122735, AF245447, AL136701, BC010671, EF107108, AK000599, AK300541, AC022154, BC006161
Ensembl: ENSG00000063176
KO: hsa:56848
Nucleutide sequences
EMBL-CDS: ABK81123.1, BAG62249.1, AAH10671.1, CAB66636.1, AAH06161.1, AAF74124.1, BAA91280.1, EAW52371.1, EAW52369.1, EAW52370.1, EAW52367.1, BAG53695.1
Gene_ORFName: hCG_15274, hCG_15274
Ensembl_TRS: ENST00000245222, ENST00000599748, ENST00000600537, ENST00000598088, ENST00000340932
Protein sequencees
Ensembl_PRO: ENSP00000245222, ENSP00000471205, ENSP00000469158, ENSP00000470092, ENSP00000341091
RefSeq: XP_011525435.1, XP_016882497.1, NP_001191088.1, NP_001191087.1, XP_016882499.1, NP_001230805.1, NP_001191089.1, XP_006723355.1, XP_011525436.1, NP_064511.2
Others
UniRef100: UniRef100_Q9NRA0, UniRef100_E9PCV4, UniRef100_B3KV83
UniRef90: UniRef90_Q9NRA0
UniRef50: UniRef50_Q9NRA0
UniGene: Hs.528006
CCDS: CCDS12727.1, CCDS59404.1, CCDS59405.1

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研究热度

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