| Type | Description |
|---|---|
| Definition | aldehyde dehydrogenase family 1, subfamily A3 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 11:31:00 | Study using human SH-SY5Y neuroblastoma and 293T cells and transgenic mouse model show that CHD7 directly regulates expression of retinoic acid synthetic enzyme ALDH1A3. Results indicate that ALDH1A3 acts with CHD7 in a common genetic pathway to regulate inner ear development, providing insights for exploration of the pathogenic mechanisms underlying CHARGE syndrome. | 29467333 |
| 2018-09-15 11:33:00 | Study in diabetic mice reports the discovery of ALDH1A3 isoform as a biomarker of dysfunctional beta cells. | 27572106 |
| 2017-11-04 11:12:00 | This study identifies Sam68 as a key regulator of neural progenitor cell self-renewal and establishes a novel link between modulation of ALDH1A3 expression and maintenance of high glycolytic metabolism in the developing cortex. | 27845622 |
| 2016-05-28 11:02:00 | Chromatin immunoprecipitation assay using RarB as the immunoprecipitation target suggests retinoic acid regulation of Aldh1a3 and Foxn1 in mice. | 26352270 |
| 2015-11-21 11:50:00 | Data suggest that expression of Aldh1a3/Raldh3 in placenta plays role in differentiation/placentation of glycogen trophoblast cells (junctional zone cells) via production of a local source of retinoic acid. | 25577283 |
| Type | IDs |
|---|---|
| Synonymous | ALDH6, RALDH3, V1 |
| Gene |
UniProtKB-ID:
AL1A3_MOUSE,
Q3UIA4_MOUSE
UniprotKB:
Q9JHW9,
Q3UIA4
UniParc:
UPI000002139A
EMBL:
AF246711,
BC058277,
AF152359,
AF253409,
AF280404,
AK147006
Ensembl:
ENSMUSG00000015134
KO:
mmu:56847
|
| Nucleutide sequences |
EMBL-CDS:
AAG33935.1,
AAF86980.1,
AAH58277.1,
AAG38488.1,
AAF67736.1,
BAE27602.1
Ensembl_TRS:
ENSMUST00000015278
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000015278
RefSeq:
NP_444310.3
|
| Others |
UniRef100:
UniRef100_Q9JHW9
UniRef90:
UniRef90_Q9JHW9
UniRef50:
UniRef50_Q9JHW9
UniGene:
Mm.140988
CCDS:
CCDS21345.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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