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5684 PSMA3

5684

PSMA3

proteasome subunit alpha 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition proteasome subunit alpha 3

研究结论

Date Results Publications
2020-05-30 11:16:00 Study identified that PSMA3 and PSMA3-AS1 in mesenchymal stem cells (MSCs) could be packaged into exosomes and transferred to myeloma cells, thus promoting proteasome inhibitor resistance through a novel exosomal PSMA3-AS1/PSMA3 signaling pathway. PSMA3-AS1 could form an RNA duplex with pre-PSMA3, which transcriptionally promoted PSMA3 expression by increasing its stability. 30610101
2018-07-21 11:37:00 High PSMA3 expression is associated with cholangiocarcinoma. 28560424
2017-09-30 11:13:00 In thyroid hemiagenesis, genomic examinations revealed the presence of four recurrent defects (three deletions and one duplication) affecting highly conservative proteasome genes PSMA1, PSMA3, and PSMD3. 28390009
2016-08-13 11:57:00 Our results provide evidence on new T1DM-susceptible loci in the PSMA3, PSMA6 and PSMC6 proteasome genes and give a new insight into the T1DM pathogenesis 26661414
2016-05-07 10:43:00 Evidence of a sex-specific association of PSMA3 genetic variants with subtypes of juvenile idiopathic arthritis. 24875235

名称对应

Type IDs
Synonymous HC8, PSC3
Gene
UniProtKB-ID: PSA3_HUMAN, A0A140VK43_HUMAN
UniprotKB: P25788, A0A140VK43
UniParc: UPI0000160D27, UPI000000D961
EMBL: BC029402, HM005583, BT006711, CH471061, BC005265, D00762, BT019715, AK315158, BC038990
Ensembl: ENSG00000100567
KO: hsa:5684
Nucleutide sequences
EMBL-CDS: AAP35357.1, BAA00659.1, EAW80719.1, AAH38990.1, AAH29402.1, BAG37603.1, AAH05265.1, AAV38520.1, AEE61180.1
Ensembl_TRS: ENST00000216455, ENST00000412908
Protein sequencees
Ensembl_PRO: ENSP00000390491, ENSP00000216455
RefSeq: NP_687033.1, NP_002779.1
Others
UniRef100: UniRef100_P25788
UniRef90: UniRef90_P25788
UniRef50: UniRef50_P25788
UniGene: Hs.558799
CCDS: CCDS45113.1, CCDS9731.1

全选

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