| Type | Description |
|---|---|
| Definition | achaete-scute family bHLH transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-02 10:43:00 | These results demonstrate that Ascl3 marks progenitors that are lineage-committed strictly to microvillar cells and Bowman's glands, and highlight the requirement for these cell types to support OE homeostasis. | 27910949 |
| 2011-07-02 10:03:00 | Ascl3 knockouts develop smaller salivary glands than wild types, but secrete saliva normally. They display a lower level of cell proliferation, consistent with their smaller size. In the absence of Ascl3, the cells maintain their progenitor function. | 21377457 |
| 2010-01-21 00:00:00 | These data demonstrate a progenitor-progeny relationship between duct cells and the acinar cell compartment, and identify a population of multipotent progenitor cells, marked by expression of Ascl3, which is capable of generating both gland cell types. | 18572159 |
| Type | IDs |
|---|---|
| Synonymous | Sgn1, bHLHa42 |
| Gene |
UniProtKB-ID:
ASCL3_MOUSE
UniprotKB:
Q9JJR7
UniParc:
UPI0000023BB8
EMBL:
BC104347,
BC104346,
AB046448,
AJ400878,
AJ277605
Ensembl:
ENSMUSG00000035951
KO:
mmu:56787
|
| Nucleutide sequences |
EMBL-CDS:
AAI04347.1,
CAC37689.1,
BAB83911.1,
AAI04348.1,
CAB92296.1
Ensembl_TRS:
ENSMUST00000035372
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037702
RefSeq:
NP_064435.1
|
| Others |
UniRef100:
UniRef100_Q9JJR7
UniRef90:
UniRef90_Q9JJR7
UniRef50:
UniRef50_Q9JJR7
UniGene:
Mm.29275
CCDS:
CCDS21737.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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