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56758 Mbnl1

56758

Mbnl1

muscleblind like splicing factor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition muscleblind like splicing factor 1

研究结论

Date Results Publications
2020-11-21 13:31:00 Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells. 32054946
2020-09-05 13:58:00 MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia. 32398749
2020-08-15 19:03:00 Study demonstrates that the RNA alternative splicing factor MBNL1, which is sequestered in nuclear RNA foci by C(C)UG microsatellite expansions in myotonic dystrophy (DM), is essential for normal thymus development and function. Mbnl1 129S1 knockout mice develop postnatal thymic hyperplasia with thymocyte accumulation. 32332745
2020-05-02 10:41:00 Mbnl1 andMbnl2 were functional at the molecular level and improved splicing events in the mouse disease model. 31754023
2020-04-18 10:08:00 Findings demonstrated that MBNL1 constitutes an emerging and autoregulatory mechanism involved in development of beige cells (Browning of white adipocytes). 31730826

名称对应

Type IDs
Synonymous Mbnl, mKIAA0428
Gene
UniProtKB-ID: MBNL1_MOUSE, Q4VA08_MOUSE, A0A0A6YWB0_MOUSE, G3X9Q0_MOUSE, Q3U570_MOUSE, Q3U581_MOUSE
UniprotKB: Q9JKP5, Q4VA08, A0A0A6YWB0, G3X9Q0, Q3U570, Q3U581
UniParc: UPI0000216F8A, UPI00005ACD16, UPI00005ACD1C, UPI0000359600, UPI0000022CB6, UPI0003D6F7DB
EMBL: AC121309, AK153848, AK153827, AF231110, AC113007, BC096600
Ensembl: ENSMUSG00000027763
KO: mmu:56758
Nucleutide sequences
EMBL-CDS: AAF72159.1, AAH96600.1, BAE32210.1, BAE32199.1
Ensembl_TRS: ENSMUST00000192607, ENSMUST00000194069, ENSMUST00000099087, ENSMUST00000191747, ENSMUST00000192807
Protein sequencees
Ensembl_PRO: ENSMUSP00000142095, ENSMUSP00000141474, ENSMUSP00000096686, ENSMUSP00000142057, ENSMUSP00000141915
RefSeq: XP_030108561.1, XP_006501857.1, XP_036019077.1, XP_017175154.1, XP_006501850.1, XP_030108571.1, NP_064391.2, XP_036019082.1, XP_030108583.1, XP_036019083.1, NP_001297443.1, XP_030108566.1, XP_006501862.1, XP_030108563.1, NP_001240642.1, XP_006501860.1, XP_030108567.1, XP_017175153.1, XP_030108580.1, XP_036019080.1, XP_006501845.1, XP_030108581.1, XP_006501856.1, XP_006501858.1, NP_001240638.1, XP_036019076.1, XP_036019085.1, XP_030108576.1, XP_030108579.1, XP_036019081.1, XP_030108573.1, NP_001240637.1, XP_017175155.1, XP_030108572.1, XP_030108577.1, XP_030108564.1, XP_006501846.1, XP_006501849.1, XP_030108575.1, XP_036019084.1, XP_036019078.1, XP_036019075.1, XP_036019074.1, XP_030108578.1, XP_036019073.1, NP_001240639.1, NP_001240640.1, XP_036019079.1, XP_030108569.1, XP_030108562.1
Others
UniRef100: UniRef100_Q3U570, UniRef100_Q9JKP5, UniRef100_G3X9Q0, UniRef100_A0A0A6YWB0
UniRef90: UniRef90_A0A0A6YWB0, UniRef90_A0A2K6G975, UniRef90_Q9JKP5, UniRef90_G3X9Q0
UniRef50: UniRef50_Q5VZF2, UniRef50_Q5ZKW9
UniGene: Mm.255723
CCDS: CCDS79917.1

全选

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