| Type | Description |
|---|---|
| Definition | tumor-associated calcium signal transducer 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:33:00 | Trop2 is upregulated in the transition to dysplasia in the metaplastic gastric mucosa. | 32432338 |
| 2015-07-25 10:27:00 | studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins. | 25523132 |
| 2012-12-22 11:14:00 | Trop2 is a regulator of self-renewal, proliferation, and transformation | 23070813 |
| 2012-09-01 10:41:00 | TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development. | 22194864 |
| 2012-06-23 10:19:00 | these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas. | 21970857 |
| Type | IDs |
|---|---|
| Synonymous | C80403, EGP-1, GA733-1, Ly97, TROP2 |
| Gene |
UniProtKB-ID:
TACD2_MOUSE
UniprotKB:
Q8BGV3
UniParc:
UPI0000022153
EMBL:
AK076410,
CH466523,
Y08830,
AK077370,
BC117720,
AK085753,
BC117719
Ensembl:
ENSMUSG00000051397
KO:
mmu:56753
|
| Nucleutide sequences |
EMBL-CDS:
EDK98807.1,
BAC36328.1,
BAC39531.1,
CAA70063.1,
AAI17721.1,
AAI17720.1,
BAC36773.1
Ensembl_TRS:
ENSMUST00000058178
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000060099
RefSeq:
NP_064431.2
|
| Others |
UniRef100:
UniRef100_Q8BGV3
UniRef90:
UniRef90_Q8BGV3
UniRef50:
UniRef50_P09758
UniGene:
Mm.439913
CCDS:
CCDS20221.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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