| Type | Description |
|---|---|
| Definition | TSC complex subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 10:27:00 | The lack of Tsc2 also delayed axonal development and caused aberrant tract fasciculation, corresponding to the abnormal expression of genes involved in axon navigation. | 31932427 |
| 2018-07-28 11:31:00 | The gene expression profiles of WT and tsc2(+/-) larvae revealed 117 differentially expressed genes (DEGs), while between WT and tsc2(-/-) larvae and tsc2(+/-) and tsc2(-/-) larvae there were 1414 and 1079 DEGs, respectively. Pathway enrichment analysis from the WT and tsc2(-/-) DEGs, identified 14 enriched pathways from the up-regulated genes and 6 enriched pathways from the down-regulated genes. | 28888969 |
| 2013-10-26 12:40:00 | This is the first report using an animal model to show interactions between tsc2, mTORC1 and p53 during tumorigenesis. | 23580196 |
| 2011-06-18 10:56:00 | These results demonstrate a highly conserved role of tsc2 in zebrafish and establish a new animal model for studies of Tuberous sclerosis complex. | 20959633 |
| Type | IDs |
|---|---|
| Synonymous | fc16b02, tuberin, wu:fc16b02 |
| Gene |
UniProtKB-ID:
A0A0G2KHX4_DANRE
UniprotKB:
A0A0G2KHX4
UniParc:
UPI00062E313A
EMBL:
CABZ01113996,
FO681319,
FQ311887,
CABZ01043818,
CABZ01113995,
CABZ01043817
Ensembl:
ENSDARG00000103125
KO:
dre:567524
|
| Nucleutide sequences |
Ensembl_TRS:
ENSDART00000158948
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000131915
RefSeq:
XP_021331273.1,
NP_001315330.1,
XP_021331269.1,
XP_021331268.1,
XP_021331278.1
|
| Others |
UniRef100:
UniRef100_A0A0G2KHX4
UniRef90:
UniRef90_A0A0G2KHX4
UniRef50:
UniRef50_A0A286Y892
UniGene:
Dr.35866,
Dr.156471
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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